Cardiac Mechanoenergetics in Patients with Acute Myocardial Infarction: From Pressure-Volume Loop Diagram Related to Cardiac Oxygen Consumption

Michinari Hieda, Yoichi Goto

Research output: Contribution to journalReview article

Abstract

Acute myocardial infarction (AMI) results in significant changes in cardiac structure and functions, leading to left ventricular remodeling and subsequent systolic and diastolic dysfunction. To improve current approaches in diagnoses, treatments, and prevention of cardiovascular diseases, a better understanding of cardiac mechanoenergetics, including systolic performance and energy demand, becomes paramount. In this review, we summarize cardiac mechanics, cardiac energetics, and their relationship in complications related to AMI using 2 important physiologic frameworks, pressure-volume loops and the VO2-pressure-volume area relationship diagram, as they are powerful tools for understanding physiologic behavior and mechanoenergetics of the left ventricle.

Original languageEnglish
Pages (from-to)255-269
Number of pages15
JournalHeart Failure Clinics
Volume16
Issue number3
DOIs
Publication statusPublished - Jul 2020

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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