Cardiac sarcoidosis concomitant with large-vessel aortitis detected by 18F-fluorodeoxyglucose positron emission tomography

Research output: Contribution to journalArticle

Abstract

We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis. FDG-PET is a useful tool for detecting cardiac sarcoidosis concomitant with large-vessel aortitis and monitoring the effectiveness of immunosuppressive therapy.

Original languageEnglish
Pages (from-to)1601-1604
Number of pages4
JournalInternal Medicine
Volume57
Issue number11
DOIs
Publication statusPublished - Jan 1 2018

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Aortitis
Fluorodeoxyglucose F18
Sarcoidosis
Positron-Emission Tomography
Immunosuppressive Agents
Prednisolone
Iliac Artery
Methotrexate
Therapeutics
Recurrence

All Science Journal Classification (ASJC) codes

  • Internal Medicine

Cite this

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title = "Cardiac sarcoidosis concomitant with large-vessel aortitis detected by 18F-fluorodeoxyglucose positron emission tomography",
abstract = "We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis. FDG-PET is a useful tool for detecting cardiac sarcoidosis concomitant with large-vessel aortitis and monitoring the effectiveness of immunosuppressive therapy.",
author = "Yoshihiro Higuchi and yasutaka kimoto and Rika Tanoue and Tomotake Tokunou and Kenichiro Tomonari and Toyoki Maeda and Takahiko Horiuchi",
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T1 - Cardiac sarcoidosis concomitant with large-vessel aortitis detected by 18F-fluorodeoxyglucose positron emission tomography

AU - Higuchi, Yoshihiro

AU - kimoto, yasutaka

AU - Tanoue, Rika

AU - Tokunou, Tomotake

AU - Tomonari, Kenichiro

AU - Maeda, Toyoki

AU - Horiuchi, Takahiko

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AB - We herein report a case of concurrent cardiac sarcoidosis and large-vessel aortitis detected by18F-fluorodeoxyglucose positron emission tomography (FDG-PET) and followed up during immunosuppressive therapy. After high-dose prednisolone administration (1 mg/kg), serial FDG-PET showed that almost all of the abnormal FDG uptake in the heart and extracardiac region, including the abdominal to bilateral iliac arteries, had been disappeared. During the tapering of prednisolone, additive methotrexate therapy was needed to treat the recurrence of cardiac sarcoidosis. FDG-PET is a useful tool for detecting cardiac sarcoidosis concomitant with large-vessel aortitis and monitoring the effectiveness of immunosuppressive therapy.

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