Cardiomyopathy secondary to systemic triglyceride storage disease

Fumio Terasaki, Keishiro Kawamura, Makoto Okabe, Tetsuya Hayashi, Hirofumi Deguchi, Shin Ichi Ando, Makoto Usui, Takahiro Matsumoto, Kensuke Egashira, Akira Takeshita

Research output: Contribution to journalArticle

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Abstract

Ultrastructural changes of a biopsied myocardium were observed by transmission electron microscopy in a patient with cardiomyopathy secondary to systemic triglyceride storage disease with Jordans' anomaly. There were many lipid droplets in the cardiocytes, and lipofuscin and mitochondria were increased. The volume fraction of myofibrils in the cardiocytes decreased because of an abundance of lipid droplets and mitochondriosis. Myocardial contractility may have been reduced by myofibrillar scarcity and low energy production resulting from an abnormality in the metabolism of fatty acids in the cardiocytes.

Original languageEnglish
Pages (from-to)88-91
Number of pages4
JournalMedical Molecular Morphology
Volume30
Issue number2
DOIs
Publication statusPublished - 1997

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Molecular Biology

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  • Cite this

    Terasaki, F., Kawamura, K., Okabe, M., Hayashi, T., Deguchi, H., Ando, S. I., Usui, M., Matsumoto, T., Egashira, K., & Takeshita, A. (1997). Cardiomyopathy secondary to systemic triglyceride storage disease. Medical Molecular Morphology, 30(2), 88-91. https://doi.org/10.1007/BF01545087