Cardiomyopathy secondary to systemic triglyceride storage disease

Fumio Terasaki, Keishiro Kawamura, Makoto Okabe, Tetsuya Hayashi, Hirofumi Deguchi, Shin Ichi Ando, Makoto Usui, Takahiro Matsumoto, Kensuke Egashira, Akira Takeshita

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)


    Ultrastructural changes of a biopsied myocardium were observed by transmission electron microscopy in a patient with cardiomyopathy secondary to systemic triglyceride storage disease with Jordans' anomaly. There were many lipid droplets in the cardiocytes, and lipofuscin and mitochondria were increased. The volume fraction of myofibrils in the cardiocytes decreased because of an abundance of lipid droplets and mitochondriosis. Myocardial contractility may have been reduced by myofibrillar scarcity and low energy production resulting from an abnormality in the metabolism of fatty acids in the cardiocytes.

    Original languageEnglish
    Pages (from-to)88-91
    Number of pages4
    JournalMedical Molecular Morphology
    Issue number2
    Publication statusPublished - 1997

    All Science Journal Classification (ASJC) codes

    • Pathology and Forensic Medicine
    • Molecular Biology


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