Carotid atherosclerosis and cardiovascular risk factors: A comparison of residents of a rural area of Okinawa with residents of a typical suburban area of Fukuoka, Japan

Masafumi Tatsukawa, Yasunori Sawayama, Naoyasu Maeda, Kyoko Okada, Norihiro Furusyo, Seizaburo Kashiwagi, Jun Hayashi

Research output: Contribution to journalArticle

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Abstract

Areas of Japan are known worldwide for the longevity of their residents. Okinawa has the highest longevity in Japan and a low rate of death due to cardiovascular disease. We investigated carotid atherosclerotic (CA) risk factors in islands of I city in Okinawa prefecture and compared them with K town, a suburban area of Fukuoka prefecture in Kyushu, to determine the relationship between cardiovascular risk factors and carotid atherosclerosis. We investigated conventional cardiovascular risk factors in 1078 I city residents (375 men, mean age 63.7 and 703 women, mean age 60.0) in 2000 and 2364 K town residents (676 men, mean age 57.1 and 1688 women, mean age 53.0) in 1999. Carotid atherosclerosis was assessed by mean intima-media thickness (IMT) by B-mode ultrasound. The mean IMT was significantly lower in the residents of I city than in those of K town (P<0.05). Total cholesterol (TC) and low-density-lipoprotein cholesterol (LDL-C) levels and smoking rate were also lower in I city than in K town. Body mass index (BMI) and triglyceride (TG) level were higher in I city than in K town. In I city, multiple regression analysis found independent relationships between carotid atherosclerosis and age, sex (male), hypertension, LDL cholesterol, high-density-lipoprotein cholesterol (HDL-C), and diabetes. The lower mean IMT is probably related to a lower lifetime burden of atherosclerotic risk factors, which may in turn be related to the longevity of Okinawa residents. BMI was not a cardiovascular risk factor, although LDL cholesterol was a common important risk factor.

Original languageEnglish
Pages (from-to)337-343
Number of pages7
JournalAtherosclerosis
Volume172
Issue number2
DOIs
Publication statusPublished - Jan 1 2004

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Carotid Artery Diseases
Japan
LDL Cholesterol
Body Mass Index
Islands
HDL Cholesterol
Triglycerides
Cardiovascular Diseases
Smoking
Cholesterol
Regression Analysis
Hypertension
Mortality

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

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Carotid atherosclerosis and cardiovascular risk factors : A comparison of residents of a rural area of Okinawa with residents of a typical suburban area of Fukuoka, Japan. / Tatsukawa, Masafumi; Sawayama, Yasunori; Maeda, Naoyasu; Okada, Kyoko; Furusyo, Norihiro; Kashiwagi, Seizaburo; Hayashi, Jun.

In: Atherosclerosis, Vol. 172, No. 2, 01.01.2004, p. 337-343.

Research output: Contribution to journalArticle

Tatsukawa, Masafumi ; Sawayama, Yasunori ; Maeda, Naoyasu ; Okada, Kyoko ; Furusyo, Norihiro ; Kashiwagi, Seizaburo ; Hayashi, Jun. / Carotid atherosclerosis and cardiovascular risk factors : A comparison of residents of a rural area of Okinawa with residents of a typical suburban area of Fukuoka, Japan. In: Atherosclerosis. 2004 ; Vol. 172, No. 2. pp. 337-343.
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