Carving of protein crystal by high-speed micro-bubble jet using micro-fluidic platform

S. Takasawa, T. Syu, Y. Yamanishi

Research output: Contribution to journalConference articlepeer-review

Abstract

This paper reports a novel micro-fluidic platform for carving protein crystal with electrically driven high-speed mono-dispersed micro-bubble jet. This minimally invasive micro-processing method overcomes the difficulties of processing, holding and positioning fragile material such as protein crystal underwater. The combination of using electrically-induced micro-bubble knife and microfluidic channel provide effective carving of protein crystal by ablation crystal and draining of chips by free vortex flow in microchannel. Three-dimensional positioning of crystal was sufficiently achieved by the configuration of effective micro-fluidic channels. The protein crystal can be carved to the desired shape to fit to X-ray analysis effectively. It seemed that it has potential to contribute to more precise protein analysis

Original languageEnglish
Article number7050933
Pages (from-to)242-244
Number of pages3
JournalProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume2015-February
Issue numberFebruary
DOIs
Publication statusPublished - Feb 26 2015
Externally publishedYes
Event2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal
Duration: Jan 18 2015Jan 22 2015

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Mechanical Engineering
  • Electrical and Electronic Engineering

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