Abstract
This paper reports a novel micro-fluidic platform for carving protein crystal with electrically driven high-speed mono-dispersed micro-bubble jet. This minimally invasive micro-processing method overcomes the difficulties of processing, holding and positioning fragile material such as protein crystal underwater. The combination of using electrically-induced micro-bubble knife and microfluidic channel provide effective carving of protein crystal by ablation crystal and draining of chips by free vortex flow in microchannel. Three-dimensional positioning of crystal was sufficiently achieved by the configuration of effective micro-fluidic channels. The protein crystal can be carved to the desired shape to fit to X-ray analysis effectively. It seemed that it has potential to contribute to more precise protein analysis
Original language | English |
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Article number | 7050933 |
Pages (from-to) | 242-244 |
Number of pages | 3 |
Journal | Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) |
Volume | 2015-February |
Issue number | February |
DOIs | |
Publication status | Published - Feb 26 2015 |
Externally published | Yes |
Event | 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: Jan 18 2015 → Jan 22 2015 |
All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Mechanical Engineering
- Electrical and Electronic Engineering