Abstract
This paper reports a novel micro-fluidic platform for carving protein crystal with electrically driven high-speed mono-dispersed micro-bubble jet. This minimally invasive micro-processing method overcomes the difficulties of processing, holding and positioning fragile material such as protein crystal underwater. The combination of using electrically-induced micro-bubble knife and microfluidic channel provide effective carving of protein crystal by ablation crystal and draining of chips by free vortex flow in microchannel. Three-dimensional positioning of crystal was sufficiently achieved by the configuration of effective micro-fluidic channels. The protein crystal can be carved to the desired shape to fit to X-ray analysis effectively. It seemed that it has potential to contribute to more precise protein analysis
| Original language | English |
|---|---|
| Article number | 7050933 |
| Pages (from-to) | 242-244 |
| Number of pages | 3 |
| Journal | Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) |
| Volume | 2015-February |
| Issue number | February |
| DOIs | |
| Publication status | Published - Feb 26 2015 |
| Externally published | Yes |
| Event | 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: Jan 18 2015 → Jan 22 2015 |
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All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Mechanical Engineering
- Electrical and Electronic Engineering
Cite this
Carving of protein crystal by high-speed micro-bubble jet using micro-fluidic platform. / Takasawa, S.; Syu, T.; Yamanishi, Y.
In: Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), Vol. 2015-February, No. February, 7050933, 26.02.2015, p. 242-244.Research output: Contribution to journal › Conference article
}
TY - JOUR
T1 - Carving of protein crystal by high-speed micro-bubble jet using micro-fluidic platform
AU - Takasawa, S.
AU - Syu, T.
AU - Yamanishi, Y.
PY - 2015/2/26
Y1 - 2015/2/26
N2 - This paper reports a novel micro-fluidic platform for carving protein crystal with electrically driven high-speed mono-dispersed micro-bubble jet. This minimally invasive micro-processing method overcomes the difficulties of processing, holding and positioning fragile material such as protein crystal underwater. The combination of using electrically-induced micro-bubble knife and microfluidic channel provide effective carving of protein crystal by ablation crystal and draining of chips by free vortex flow in microchannel. Three-dimensional positioning of crystal was sufficiently achieved by the configuration of effective micro-fluidic channels. The protein crystal can be carved to the desired shape to fit to X-ray analysis effectively. It seemed that it has potential to contribute to more precise protein analysis
AB - This paper reports a novel micro-fluidic platform for carving protein crystal with electrically driven high-speed mono-dispersed micro-bubble jet. This minimally invasive micro-processing method overcomes the difficulties of processing, holding and positioning fragile material such as protein crystal underwater. The combination of using electrically-induced micro-bubble knife and microfluidic channel provide effective carving of protein crystal by ablation crystal and draining of chips by free vortex flow in microchannel. Three-dimensional positioning of crystal was sufficiently achieved by the configuration of effective micro-fluidic channels. The protein crystal can be carved to the desired shape to fit to X-ray analysis effectively. It seemed that it has potential to contribute to more precise protein analysis
UR - http://www.scopus.com/inward/record.url?scp=84931043257&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84931043257&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2015.7050933
DO - 10.1109/MEMSYS.2015.7050933
M3 - Conference article
AN - SCOPUS:84931043257
VL - 2015-February
SP - 242
EP - 244
JO - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
JF - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SN - 1084-6999
IS - February
M1 - 7050933
ER -