Abstract
Nickel(II) acetate tetrahydrate works as catalyst to activate nucleophile precursors in Michael addition reactions. Use of alcohol media is essential for the high catalytic activation of nucleophile precursors. Catalytic enantioselective reactions using a chiral nickel(II) acetate tetrahydrate between dimedone and α,β-unsaturated amide acceptors provide a useful synthetic access to enantiomers of enol lactones through the carbon-carbon bond formation.
Original language | English |
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Pages (from-to) | 5105-5107 |
Number of pages | 3 |
Journal | Tetrahedron Letters |
Volume | 49 |
Issue number | 34 |
DOIs | |
Publication status | Published - Aug 18 2008 |
All Science Journal Classification (ASJC) codes
- Biochemistry
- Drug Discovery
- Organic Chemistry