Catalytic asymmetric addition of organolithiums to aldimines

Kiyoshi Tomioka, Isao Inoue, Mitsuru Shindo, Kenji Koga

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

An asymmetric 1,2-addition of organolithiums to imines (1) was catalyzed by a substoichiometric amount (0.05-0.3 equivalent) of a chiral aminoether (2) to provide the corresponding optically active amines (3).

Original languageEnglish
Pages (from-to)3095-3098
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number26
DOIs
Publication statusPublished - Jun 24 1991
Externally publishedYes

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Imines
Amines

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Catalytic asymmetric addition of organolithiums to aldimines. / Tomioka, Kiyoshi; Inoue, Isao; Shindo, Mitsuru; Koga, Kenji.

In: Tetrahedron Letters, Vol. 32, No. 26, 24.06.1991, p. 3095-3098.

Research output: Contribution to journalArticle

Tomioka, Kiyoshi ; Inoue, Isao ; Shindo, Mitsuru ; Koga, Kenji. / Catalytic asymmetric addition of organolithiums to aldimines. In: Tetrahedron Letters. 1991 ; Vol. 32, No. 26. pp. 3095-3098.
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