Catalytic asymmetric and chemoselective aerobic oxidation: Kinetic resolution of sec-alcohols

Kouta Masutani, Tatsuya Uchida, Ryo Irie, Tsutomu Katsuki

Research output: Contribution to journalArticle

137 Citations (Scopus)

Abstract

Optically active (nitroso)(salen)ruthenium(II) chloride (2) was found to be an efficient catalyst for aerobic oxidation of racemic secondary alcohols under irradiation with a halogen or fluorescent lamp, which proceeded with good enantiomer-differentiation (k(rel) = 11-20). Furthermore, no epoxidation was observed in the oxidation of racemic 4-phenyl-3-buten-2-ol. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)5119-5123
Number of pages5
JournalTetrahedron Letters
Volume41
Issue number26
DOIs
Publication statusPublished - Jun 24 2000

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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