Catalytic asymmetric hydrogenation of naphthalenes

Ryoichi Kuwano, Ryuichi Morioka, Manabu Kashiwabara, Nao Kameyama

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Vanishing aromaticity: A chiral ruthenium complex catalyzes the hydrogenation of 2,6- or 2,7-disubstituted naphthalenes to give chiral tetralins with up to 92 % ee. The chiral catalyst is applicable to the regio- and enantioselective reduction of 6-substituted 2-alkoxynaphthalenes and preferentially hydrogenates the alkoxy-substituted arene rings.

Original languageEnglish
Pages (from-to)4136-4139
Number of pages4
JournalAngewandte Chemie - International Edition
Volume51
Issue number17
DOIs
Publication statusPublished - Apr 23 2012

Fingerprint

Tetrahydronaphthalenes
Naphthalenes
Ruthenium
Naphthalene
Hydrogenation
Catalysts
alkoxyl radical

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

Cite this

Catalytic asymmetric hydrogenation of naphthalenes. / Kuwano, Ryoichi; Morioka, Ryuichi; Kashiwabara, Manabu; Kameyama, Nao.

In: Angewandte Chemie - International Edition, Vol. 51, No. 17, 23.04.2012, p. 4136-4139.

Research output: Contribution to journalArticle

Kuwano, Ryoichi ; Morioka, Ryuichi ; Kashiwabara, Manabu ; Kameyama, Nao. / Catalytic asymmetric hydrogenation of naphthalenes. In: Angewandte Chemie - International Edition. 2012 ; Vol. 51, No. 17. pp. 4136-4139.
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