Catalytic hydrogenation of carboxamides and esters by well-defined Cp*Ru complexes bearing a protic amine ligand

Masato Ito; Takashi Ootsuka; Ryo Watari; Akira Shiibashi; Akio Himizu; Takao Ikariya

doi:10.1021/ja1117254

Catalytic hydrogenation of carboxamides and esters by well-defined Cp*Ru complexes bearing a protic amine ligand

Masato Ito, Takashi Ootsuka, Ryo Watari, Akira Shiibashi, Akio Himizu, Takao Ikariya

Department of Applied Molecular Chemistry

Research output: Contribution to journal › Article › peer-review

170 Citations (Scopus)

Abstract

A novel catalytic method for the straightforward hydrogenation of carboxamides and esters to primary alcohols has been developed. Chiral modification in the ligand sphere of the well-defined Cp*Ru catalyst molecule opens up a new possibility for the development of an enantioselective hydrogenation of racemic substrates via dynamic kinetic resolution.

Original language	English
Pages (from-to)	4240-4242
Number of pages	3
Journal	Journal of the American Chemical Society
Volume	133
Issue number	12
DOIs	https://doi.org/10.1021/ja1117254
Publication status	Published - Mar 30 2011

All Science Journal Classification (ASJC) codes

Catalysis
Chemistry(all)
Biochemistry
Colloid and Surface Chemistry

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10.1021/ja1117254

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abstract = "A novel catalytic method for the straightforward hydrogenation of carboxamides and esters to primary alcohols has been developed. Chiral modification in the ligand sphere of the well-defined Cp*Ru catalyst molecule opens up a new possibility for the development of an enantioselective hydrogenation of racemic substrates via dynamic kinetic resolution.",

author = "Masato Ito and Takashi Ootsuka and Ryo Watari and Akira Shiibashi and Akio Himizu and Takao Ikariya",

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AU - Ito, Masato

AU - Ootsuka, Takashi

AU - Watari, Ryo

AU - Shiibashi, Akira

AU - Himizu, Akio

AU - Ikariya, Takao

PY - 2011/3/30

Y1 - 2011/3/30

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AB - A novel catalytic method for the straightforward hydrogenation of carboxamides and esters to primary alcohols has been developed. Chiral modification in the ligand sphere of the well-defined Cp*Ru catalyst molecule opens up a new possibility for the development of an enantioselective hydrogenation of racemic substrates via dynamic kinetic resolution.

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Catalytic hydrogenation of carboxamides and esters by well-defined Cp*Ru complexes bearing a protic amine ligand

Abstract

All Science Journal Classification (ASJC) codes

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