Catalytic hydrogenation of carboxamides and esters by well-defined Cp*Ru complexes bearing a protic amine ligand

Masato Ito, Takashi Ootsuka, Ryo Watari, Akira Shiibashi, Akio Himizu, Takao Ikariya

Research output: Contribution to journalArticle

141 Citations (Scopus)

Abstract

A novel catalytic method for the straightforward hydrogenation of carboxamides and esters to primary alcohols has been developed. Chiral modification in the ligand sphere of the well-defined Cp*Ru catalyst molecule opens up a new possibility for the development of an enantioselective hydrogenation of racemic substrates via dynamic kinetic resolution.

Original languageEnglish
Pages (from-to)4240-4242
Number of pages3
JournalJournal of the American Chemical Society
Volume133
Issue number12
DOIs
Publication statusPublished - Mar 30 2011

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Bearings (structural)
Hydrogenation
Amines
Esters
Ligands
Alcohols
Catalysts
Molecules
Kinetics
Substrates

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Catalytic hydrogenation of carboxamides and esters by well-defined Cp*Ru complexes bearing a protic amine ligand. / Ito, Masato; Ootsuka, Takashi; Watari, Ryo; Shiibashi, Akira; Himizu, Akio; Ikariya, Takao.

In: Journal of the American Chemical Society, Vol. 133, No. 12, 30.03.2011, p. 4240-4242.

Research output: Contribution to journalArticle

Ito, Masato ; Ootsuka, Takashi ; Watari, Ryo ; Shiibashi, Akira ; Himizu, Akio ; Ikariya, Takao. / Catalytic hydrogenation of carboxamides and esters by well-defined Cp*Ru complexes bearing a protic amine ligand. In: Journal of the American Chemical Society. 2011 ; Vol. 133, No. 12. pp. 4240-4242.
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