Abstract
Purpose: To investigate the interval between low-dose radiotherapy and radiation-induced cataracts, and the factors affecting this interval, in patients with lymphoproliferative disease of the ocular adnexa. Methods: A retrospective case series of 73 eyes of 59 patients who underwent radiotherapy from 1996 to 2005 with total doses ranging from 24 to 30 Gy was conducted. We investigated the relationships between the radiation-associated cataract formation intervals and age, gender, diabetes, and the use of corticosteroids. Results: The mean interval was 36 months. None of the patients with lens shield developed cataracts. Age was inversely and significantly and gender was not significantly associated with the interval from first radiotherapy to cataract occurrence. The intervals did not differ significantly according to the presence of diabetes and corticosteroid therapy. Conclusions: The mean interval from the start of radiation therapy to radiation-related cataract formation was 36 months and age was a significant factor affecting this interval.
| Original language | English |
|---|---|
| Pages (from-to) | 702-706 |
| Number of pages | 5 |
| Journal | Seminars in Ophthalmology |
| Volume | 32 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Nov 2 2017 |
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All Science Journal Classification (ASJC) codes
- Ophthalmology
Cite this
Cataracts after Low-Dose Radiotherapy for Lymphoproliferative Disease of the Ocular Adnexa. / Hashimoto, Sawako; Yoshikawa, Hiroshi; Miyagi, Michiko; Onishi, Yoko; Saiji, Ohga; Asai, Kaori; Ishibashi, Tatsuro.
In: Seminars in Ophthalmology, Vol. 32, No. 6, 02.11.2017, p. 702-706.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Cataracts after Low-Dose Radiotherapy for Lymphoproliferative Disease of the Ocular Adnexa
AU - Hashimoto, Sawako
AU - Yoshikawa, Hiroshi
AU - Miyagi, Michiko
AU - Onishi, Yoko
AU - Saiji, Ohga
AU - Asai, Kaori
AU - Ishibashi, Tatsuro
PY - 2017/11/2
Y1 - 2017/11/2
N2 - Purpose: To investigate the interval between low-dose radiotherapy and radiation-induced cataracts, and the factors affecting this interval, in patients with lymphoproliferative disease of the ocular adnexa. Methods: A retrospective case series of 73 eyes of 59 patients who underwent radiotherapy from 1996 to 2005 with total doses ranging from 24 to 30 Gy was conducted. We investigated the relationships between the radiation-associated cataract formation intervals and age, gender, diabetes, and the use of corticosteroids. Results: The mean interval was 36 months. None of the patients with lens shield developed cataracts. Age was inversely and significantly and gender was not significantly associated with the interval from first radiotherapy to cataract occurrence. The intervals did not differ significantly according to the presence of diabetes and corticosteroid therapy. Conclusions: The mean interval from the start of radiation therapy to radiation-related cataract formation was 36 months and age was a significant factor affecting this interval.
AB - Purpose: To investigate the interval between low-dose radiotherapy and radiation-induced cataracts, and the factors affecting this interval, in patients with lymphoproliferative disease of the ocular adnexa. Methods: A retrospective case series of 73 eyes of 59 patients who underwent radiotherapy from 1996 to 2005 with total doses ranging from 24 to 30 Gy was conducted. We investigated the relationships between the radiation-associated cataract formation intervals and age, gender, diabetes, and the use of corticosteroids. Results: The mean interval was 36 months. None of the patients with lens shield developed cataracts. Age was inversely and significantly and gender was not significantly associated with the interval from first radiotherapy to cataract occurrence. The intervals did not differ significantly according to the presence of diabetes and corticosteroid therapy. Conclusions: The mean interval from the start of radiation therapy to radiation-related cataract formation was 36 months and age was a significant factor affecting this interval.
UR - http://www.scopus.com/inward/record.url?scp=84978496173&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84978496173&partnerID=8YFLogxK
U2 - 10.3109/08820538.2016.1170159
DO - 10.3109/08820538.2016.1170159
M3 - Article
C2 - 27420339
AN - SCOPUS:84978496173
VL - 32
SP - 702
EP - 706
JO - Seminars in Ophthalmology
JF - Seminars in Ophthalmology
SN - 0882-0538
IS - 6
ER -