Abstract
A 39-year-old male was referred to our hospital in June, 1993, because of leukocytosis. Physical examinations showed massive splenomegaly without any lymphadenopathy. The white blood cell count was 13,800/microliters with 87% morphologically mature lymphocytes. Bone marrow aspirate revealed hypercellularity with 67% lymphocytes morphologically similar to peripheral lymphocytes. The lymphocytes displayed monoclonal rearrangements of immunoglobulin genes and the phenotype of CD5-CD19+CD20+ CD21+ and Smlg+. Splenectomy was effective against neutropenia and thromboytopenia. The clinical and laboratory findings of this case were unusual compared to those of typical B-CLL in massive splenomegaly, no lymphadenopathy and CD5-phenotype, suggesting the heterogeneity of B-CLL.
| Original language | English |
|---|---|
| Pages (from-to) | 1230-1232 |
| Number of pages | 3 |
| Journal | [Rinshō ketsueki] The Japanese journal of clinical hematology |
| Volume | 36 |
| Issue number | 10 |
| Publication status | Published - Oct 1995 |
| Externally published | Yes |
All Science Journal Classification (ASJC) codes
- Medicine(all)