Cell deformability measurement device for labeled-free cancer cells discriminating using ionic current detection

T. Suzuki, N. Kaji, H. Yasaki, T. Yasui, Y. Baba

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, we have developed ionic current detection device that can discriminate cells by measurement of cell deformability for detecting circulating tumor cells (CTC). We successfully discriminated CTC model from leukocyte model without any fluorescent labels by using the device. Moreover, we could detect relatively small CTCs compared to blood cells, which are difficult to detect by conventional filter devices. This device is expected as a new cancer diagnostic device that is simple and highly sensitive.

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages347-348
Number of pages2
ISBN (Electronic)9781510897571
Publication statusPublished - Jan 1 2018
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: Nov 11 2018Nov 15 2018

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume1

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
CountryTaiwan, Province of China
CityKaohsiung
Period11/11/1811/15/18

All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Bioengineering
  • Chemical Engineering (miscellaneous)
  • Control and Systems Engineering

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  • Cite this

    Suzuki, T., Kaji, N., Yasaki, H., Yasui, T., & Baba, Y. (2018). Cell deformability measurement device for labeled-free cancer cells discriminating using ionic current detection. In 22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 (pp. 347-348). (22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018; Vol. 1). Chemical and Biological Microsystems Society.