Cell fatigue test

W. Fukui; M. Kaneko; S. Sakuma; F. Arai

doi:10.1109/MEMSYS.2013.6474423

Cell fatigue test

W. Fukui, M. Kaneko, S. Sakuma, F. Arai

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Citations (Scopus)

Abstract

A new concept of 'Cell Fatigue Test' is proposed. By reciprocating a cell across the throat of a micro channel repeatedly, the dynamic behavior of cell deformation is measured. We define a new index of fatigue life of cells as the number of reciprocatory motions leading to the prescribed recovery ratio. The test system is composed of a piezoelectric (PZT) actuator, a high speed vision sensor and a micro channel with a throat. Preliminary experiments were conducted by using Red Blood Cells (RBCs). The result shows that there is great variability in fatigue life of cells and the hues of cell membrane drastically change as the number of stress cycles increase.

Original language	English
Title of host publication	IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Pages	1025-1028
Number of pages	4
DOIs	https://doi.org/10.1109/MEMSYS.2013.6474423
Publication status	Published - 2013
Externally published	Yes
Event	IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 - Taipei, Taiwan, Province of China Duration: Jan 20 2013 → Jan 24 2013

Publication series

Name	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
ISSN (Print)	1084-6999

Other

Other	IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013
Country/Territory	Taiwan, Province of China
City	Taipei
Period	1/20/13 → 1/24/13

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

Access to Document

10.1109/MEMSYS.2013.6474423

Cite this

Fukui, W, Kaneko, M, Sakuma, S & Arai, F 2013, Cell fatigue test. in IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013., 6474423, Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS), pp. 1025-1028, IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013, Taipei, Taiwan, Province of China, 1/20/13. https://doi.org/10.1109/MEMSYS.2013.6474423

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abstract = "A new concept of 'Cell Fatigue Test' is proposed. By reciprocating a cell across the throat of a micro channel repeatedly, the dynamic behavior of cell deformation is measured. We define a new index of fatigue life of cells as the number of reciprocatory motions leading to the prescribed recovery ratio. The test system is composed of a piezoelectric (PZT) actuator, a high speed vision sensor and a micro channel with a throat. Preliminary experiments were conducted by using Red Blood Cells (RBCs). The result shows that there is great variability in fatigue life of cells and the hues of cell membrane drastically change as the number of stress cycles increase.",

author = "W. Fukui and M. Kaneko and S. Sakuma and F. Arai",

note = "Copyright: Copyright 2013 Elsevier B.V., All rights reserved.; IEEE 26th International Conference on Micro Electro Mechanical Systems, MEMS 2013 ; Conference date: 20-01-2013 Through 24-01-2013",

year = "2013",

doi = "10.1109/MEMSYS.2013.6474423",

language = "English",

isbn = "9781467356558",

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AU - Kaneko, M.

AU - Sakuma, S.

AU - Arai, F.

PY - 2013

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AB - A new concept of 'Cell Fatigue Test' is proposed. By reciprocating a cell across the throat of a micro channel repeatedly, the dynamic behavior of cell deformation is measured. We define a new index of fatigue life of cells as the number of reciprocatory motions leading to the prescribed recovery ratio. The test system is composed of a piezoelectric (PZT) actuator, a high speed vision sensor and a micro channel with a throat. Preliminary experiments were conducted by using Red Blood Cells (RBCs). The result shows that there is great variability in fatigue life of cells and the hues of cell membrane drastically change as the number of stress cycles increase.

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Cell fatigue test

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