'Cell Pinball': What is the physics?

Ryo Murakami; Makoto Kaneko; Shinya Sakuma; Fumihito Arai

doi:10.1109/MEMSYS.2015.7050982

'Cell Pinball': What is the physics?

Ryo Murakami, Makoto Kaneko, Shinya Sakuma, Fumihito Arai

Research output: Contribution to journal › Conference article › peer-review

1 Citation (Scopus)

Abstract

During the deformability test of Red Blood Cell (RBC) by utilizing a micro fluidic channel, we found an interesting phenomenon where some RBCs behave just like elastic pinball with the motion in the perpendicular direction with respect to the main flow line, while most of RBCs simply move along the main flow line. This phenomenon is called 'Cell Pinball'. Through visualization, we found that the RBC being in Cell Pinball mode rotates around the perpendicular axis to the flow line and the rotating direction has one-to-one relationship with the moving direction without any exceptions. We also found that the rotating axis exists slightly behind the center of gravity with respect to the flow direction. This geometrical configuration makes an unstable condition for the cell under the fluid force, which eventually produces the motion perpendicular to the main flow line.

Original language	English
Article number	7050982
Pages (from-to)	431-434
Number of pages	4
Journal	Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Volume	2015-February
Issue number	February
DOIs	https://doi.org/10.1109/MEMSYS.2015.7050982
Publication status	Published - Feb 26 2015
Externally published	Yes
Event	2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 - Estoril, Portugal Duration: Jan 18 2015 → Jan 22 2015

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Mechanical Engineering
Electrical and Electronic Engineering

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10.1109/MEMSYS.2015.7050982

Cite this

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title = "'Cell Pinball': What is the physics?",

abstract = "During the deformability test of Red Blood Cell (RBC) by utilizing a micro fluidic channel, we found an interesting phenomenon where some RBCs behave just like elastic pinball with the motion in the perpendicular direction with respect to the main flow line, while most of RBCs simply move along the main flow line. This phenomenon is called 'Cell Pinball'. Through visualization, we found that the RBC being in Cell Pinball mode rotates around the perpendicular axis to the flow line and the rotating direction has one-to-one relationship with the moving direction without any exceptions. We also found that the rotating axis exists slightly behind the center of gravity with respect to the flow direction. This geometrical configuration makes an unstable condition for the cell under the fluid force, which eventually produces the motion perpendicular to the main flow line.",

author = "Ryo Murakami and Makoto Kaneko and Shinya Sakuma and Fumihito Arai",

note = "Publisher Copyright: {\textcopyright} 2015 IEEE. Copyright: Copyright 2015 Elsevier B.V., All rights reserved.; 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015 ; Conference date: 18-01-2015 Through 22-01-2015",

year = "2015",

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doi = "10.1109/MEMSYS.2015.7050982",

language = "English",

volume = "2015-February",

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journal = "Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)",

issn = "1084-6999",

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number = "February",

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T1 - 'Cell Pinball'

T2 - 2015 28th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2015

AU - Murakami, Ryo

AU - Kaneko, Makoto

AU - Sakuma, Shinya

AU - Arai, Fumihito

PY - 2015/2/26

Y1 - 2015/2/26

N2 - During the deformability test of Red Blood Cell (RBC) by utilizing a micro fluidic channel, we found an interesting phenomenon where some RBCs behave just like elastic pinball with the motion in the perpendicular direction with respect to the main flow line, while most of RBCs simply move along the main flow line. This phenomenon is called 'Cell Pinball'. Through visualization, we found that the RBC being in Cell Pinball mode rotates around the perpendicular axis to the flow line and the rotating direction has one-to-one relationship with the moving direction without any exceptions. We also found that the rotating axis exists slightly behind the center of gravity with respect to the flow direction. This geometrical configuration makes an unstable condition for the cell under the fluid force, which eventually produces the motion perpendicular to the main flow line.

AB - During the deformability test of Red Blood Cell (RBC) by utilizing a micro fluidic channel, we found an interesting phenomenon where some RBCs behave just like elastic pinball with the motion in the perpendicular direction with respect to the main flow line, while most of RBCs simply move along the main flow line. This phenomenon is called 'Cell Pinball'. Through visualization, we found that the RBC being in Cell Pinball mode rotates around the perpendicular axis to the flow line and the rotating direction has one-to-one relationship with the moving direction without any exceptions. We also found that the rotating axis exists slightly behind the center of gravity with respect to the flow direction. This geometrical configuration makes an unstable condition for the cell under the fluid force, which eventually produces the motion perpendicular to the main flow line.

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JO - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)

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Y2 - 18 January 2015 through 22 January 2015

ER -

'Cell Pinball': What is the physics?

Abstract

All Science Journal Classification (ASJC) codes

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