Cell to cell adhesion systems in Xenopus laevis, the South African clawed toad II: Monoclonal antibody against a novel Ca2+-dependent cell-cell adhesion glycoprotein on amphibian cells

Kazuya Nomura, T. Tajima, H. Nomura, H. Shiraishi, M. Uchida, K. Yamana

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

We isolated a mouse monoclonal antibody that disrupts Ca2+-dependent cell-cell adhesion of amphibian (Xenopus laevis) cells. When added to culture medium, the monoclonal antibody completely disrupted cell-cell adhesion of amphibian cells in monolayer culture and specifically inhibited Ca2+-dependent cell-cell adhesion of dissociated cells in reaggregation experiments. The monoclonal antibody recognized a 140 kDa cell surface glycoprotein antigenically different from the previously reported Ca2+-dependent cell-cell adhesion molecules (cadherins).

Original languageEnglish
Pages (from-to)207-212
Number of pages6
JournalCell Differentiation
Volume23
Issue number3
DOIs
Publication statusPublished - Jan 1 1988

Fingerprint

Xenopus laevis
Amphibians
Cell Adhesion
Anura
Glycoproteins
Monoclonal Antibodies
Membrane Glycoproteins
Cell Adhesion Molecules
Cadherins
Culture Media

All Science Journal Classification (ASJC) codes

  • Developmental Biology

Cite this

Cell to cell adhesion systems in Xenopus laevis, the South African clawed toad II : Monoclonal antibody against a novel Ca2+-dependent cell-cell adhesion glycoprotein on amphibian cells. / Nomura, Kazuya; Tajima, T.; Nomura, H.; Shiraishi, H.; Uchida, M.; Yamana, K.

In: Cell Differentiation, Vol. 23, No. 3, 01.01.1988, p. 207-212.

Research output: Contribution to journalArticle

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