Cell vibro-deformability

Shinya Sakuma, Keisuke Kuroda, Fumihito Arai, Makoto Kaneko

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We newly proposed the "Cell Vibro-Deformability" where cell frequency characteristics is observed by moving a single cell in microchannel periodically, with an assistance of both an online high speed camera and piezoelectric actuator. The developed system composed of a high speed pump, and an online high speed vision, and a microfluidic chip. Through experiments by using red blood cell, we obtained the frequency characteristics for cell shape. An interesting observation is that a red blood cell with normal shape is gradually folded at the entrance of narrow throat as "coffee bean" and eventually results in the shape of "boat shape" irrespective of the frequency between 1 through 20 Hz. Furthermore, the shape of RBC at the exit strongly depends upon the frequency, particularly the length becomes longer when the frequency increases.

Original languageEnglish
Title of host publication17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PublisherChemical and Biological Microsystems Society
Pages976-978
Number of pages3
ISBN (Print)9781632666246
Publication statusPublished - 2013
Externally publishedYes
Event17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013 - Freiburg, Germany
Duration: Oct 27 2013Oct 31 2013

Publication series

Name17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Volume2

Other

Other17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
CountryGermany
CityFreiburg
Period10/27/1310/31/13

All Science Journal Classification (ASJC) codes

  • Bioengineering

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