TY - GEN
T1 - Cell vibro-deformability
AU - Sakuma, Shinya
AU - Kuroda, Keisuke
AU - Arai, Fumihito
AU - Kaneko, Makoto
PY - 2013
Y1 - 2013
N2 - We newly proposed the "Cell Vibro-Deformability" where cell frequency characteristics is observed by moving a single cell in microchannel periodically, with an assistance of both an online high speed camera and piezoelectric actuator. The developed system composed of a high speed pump, and an online high speed vision, and a microfluidic chip. Through experiments by using red blood cell, we obtained the frequency characteristics for cell shape. An interesting observation is that a red blood cell with normal shape is gradually folded at the entrance of narrow throat as "coffee bean" and eventually results in the shape of "boat shape" irrespective of the frequency between 1 through 20 Hz. Furthermore, the shape of RBC at the exit strongly depends upon the frequency, particularly the length becomes longer when the frequency increases.
AB - We newly proposed the "Cell Vibro-Deformability" where cell frequency characteristics is observed by moving a single cell in microchannel periodically, with an assistance of both an online high speed camera and piezoelectric actuator. The developed system composed of a high speed pump, and an online high speed vision, and a microfluidic chip. Through experiments by using red blood cell, we obtained the frequency characteristics for cell shape. An interesting observation is that a red blood cell with normal shape is gradually folded at the entrance of narrow throat as "coffee bean" and eventually results in the shape of "boat shape" irrespective of the frequency between 1 through 20 Hz. Furthermore, the shape of RBC at the exit strongly depends upon the frequency, particularly the length becomes longer when the frequency increases.
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M3 - Conference contribution
AN - SCOPUS:84907365962
SN - 9781632666246
T3 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
SP - 976
EP - 978
BT - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
PB - Chemical and Biological Microsystems Society
T2 - 17th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2013
Y2 - 27 October 2013 through 31 October 2013
ER -