Cellular adhesiveness on implanted lenses in monkeys

Tatsuro Ishibashi; Shigeru Sugai; Toshiaki Kubota; Yoshitaka Ohnishi; Hajime Inomata

doi:10.1007/BF00920062

Cellular adhesiveness on implanted lenses in monkeys

Tatsuro Ishibashi, Shigeru Sugai, Toshiaki Kubota, Yoshitaka Ohnishi, Hajime Inomata

Kyushu University Hospital

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Abstract

Cells are known to adhere to implanted intraocular lenses (IOLs), but the mechanisms of this adhesiveness are not known. We studied cellular adhesiveness on four posterior chamber IOLs that had been implanted into monkey eyes. The animals were killed at 4 and at 7 days after lens implantation. The IOLs were removed and examined by transmission electron microscopy. At 4 days after IOL implantation, macrophages were attached to the IOL surface; at 7 days after implantation, multinucleated giant cells were attached to the IOL surface. These cells had bundles of microfilaments in the subplasmalemmal region of areas of close cell-IOL apposition. These microfilaments may play an important role in the cellular adhesiveness on the surface of implanted IOLs.

Original language	English
Pages (from-to)	356-362
Number of pages	7
Journal	Graefe's Archive for Clinical and Experimental Ophthalmology
Volume	228
Issue number	4
DOIs	https://doi.org/10.1007/BF00920062
Publication status	Published - Jul 1 1990

All Science Journal Classification (ASJC) codes

Ophthalmology
Sensory Systems
Cellular and Molecular Neuroscience

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title = "Cellular adhesiveness on implanted lenses in monkeys",

abstract = "Cells are known to adhere to implanted intraocular lenses (IOLs), but the mechanisms of this adhesiveness are not known. We studied cellular adhesiveness on four posterior chamber IOLs that had been implanted into monkey eyes. The animals were killed at 4 and at 7 days after lens implantation. The IOLs were removed and examined by transmission electron microscopy. At 4 days after IOL implantation, macrophages were attached to the IOL surface; at 7 days after implantation, multinucleated giant cells were attached to the IOL surface. These cells had bundles of microfilaments in the subplasmalemmal region of areas of close cell-IOL apposition. These microfilaments may play an important role in the cellular adhesiveness on the surface of implanted IOLs.",

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AU - Ishibashi, Tatsuro

AU - Sugai, Shigeru

AU - Kubota, Toshiaki

AU - Ohnishi, Yoshitaka

AU - Inomata, Hajime

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N2 - Cells are known to adhere to implanted intraocular lenses (IOLs), but the mechanisms of this adhesiveness are not known. We studied cellular adhesiveness on four posterior chamber IOLs that had been implanted into monkey eyes. The animals were killed at 4 and at 7 days after lens implantation. The IOLs were removed and examined by transmission electron microscopy. At 4 days after IOL implantation, macrophages were attached to the IOL surface; at 7 days after implantation, multinucleated giant cells were attached to the IOL surface. These cells had bundles of microfilaments in the subplasmalemmal region of areas of close cell-IOL apposition. These microfilaments may play an important role in the cellular adhesiveness on the surface of implanted IOLs.

AB - Cells are known to adhere to implanted intraocular lenses (IOLs), but the mechanisms of this adhesiveness are not known. We studied cellular adhesiveness on four posterior chamber IOLs that had been implanted into monkey eyes. The animals were killed at 4 and at 7 days after lens implantation. The IOLs were removed and examined by transmission electron microscopy. At 4 days after IOL implantation, macrophages were attached to the IOL surface; at 7 days after implantation, multinucleated giant cells were attached to the IOL surface. These cells had bundles of microfilaments in the subplasmalemmal region of areas of close cell-IOL apposition. These microfilaments may play an important role in the cellular adhesiveness on the surface of implanted IOLs.

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Cellular adhesiveness on implanted lenses in monkeys

Abstract

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