Central retinal artery occlusion in a patient with ANCA-negative Churg-Strauss syndrome

Yuji Kumano, Noriko Yoshida, Satoru Fukuyama, Masanori Miyazaki, Hiroshi Enaida, Takaaki Matsui

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Ocular involvement in Churg-Strauss syndrome is infrequent. We describe the case of a 54-year-old woman with eosinophilia and involvement of the respiratory tract, skin, and peripheral nervous system, fulfilling the American College of Rheumatology criteria for Churg-Strauss syndrome. The patient presented with acute, painless vision loss in her right eye. Central retinal artery occlusion (CRAO) without accompanying retinal vasculitis was diagnosed by angiographic findings and funduscopic findings of retinal whitening with a cherry-red spot. Although her antineutrophil cytoplasmic antibody (ANCA) status was negative, CRAO was thought to be an ocular manifestation of Churg-Strauss syndrome, and appropriate treatment was planned. She was treated with high-dose corticosteroids and anticoagulant therapy. Her macular edema improved, but visual recovery was poor. Specific therapy to alter inflammation, blood coagulation, and rheology reportedly plays an important role in ANCA-positive patients with Churg-Strauss syndrome who develop CRAO. Regardless of ANCA status, high-dose corticosteroids should be considered for CRAO in patients with Churg-Strauss syndrome, as discussed in this case.

Original languageEnglish
Pages (from-to)1225-1228
Number of pages4
JournalClinical Ophthalmology
Volume6
Issue number1
DOIs
Publication statusPublished - Jul 30 2012

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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