Abstract
In anaesthetized, mechanically ventilated rats with brain death induced by epidural balloon inflation, we assessed the levels of cerebral myo-inositol in three brain areas 4 h after brain death had been confirmed. The levels were measured using HPLC, along with the water content. Myo-inositol levels were significantly increased in the cerebellum (P<0.05) and decreased in the brainstem (P<0.001), compared to findings in controls. Such changes can serve as hallmarks of brain death.
Original language | English |
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Pages (from-to) | 110-112 |
Number of pages | 3 |
Journal | Legal Medicine |
Volume | 7 |
Issue number | 2 |
DOIs | |
Publication status | Published - Mar 2005 |
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine
- Issues, ethics and legal aspects