Change of sonographic findings on cervical lymph nodes before and after preoperative radiotherapy

Toru Chikui, Kenji Yuasa, Kenji Tokumori, Shigenobu Kanda, Naonobu Kunitake, Katsumasa Nakamura, Tetsuji Nagata, Akimitsu Hiraki

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The aim of this study was to assess the changes in the power Doppler sonographic findings in patients with oral cancer undergoing chemotherapy and radiotherapy. We performed US examinations on 187 cervical lymph nodes (71 metastatic and 116 reactive nodes) excised from 52 patients before and after preoperative therapy. On Power Doppler images, we calculated the vascular index (VI) and evaluated the vascular pattern. We also assessed the diagnostic power using receiver operating characteristic (ROC) curve analysis. Irradiation caused an increase of the VI and better visualization of the vessels within the lymph node in the reactive nodes; however, in the metastatic nodes, the VI was not significantly different between that before and after irradiation. When the reader observed the images before irradiation, the area under an ROC curve (Az values) observed by B-mode sonography were closely similar to those obtained by B-mode plus power Doppler sonography. With both images before and after irradiation, the Az value obtained by B-mode plus power Doppler sonography was higher than that by B-mode sonography alone. After irradiation, the enhanced Doppler signals contributed to a better visualization of the vessels and a better detection of any vascular abnormalities.

Original languageEnglish
Pages (from-to)1255-1262
Number of pages8
JournalEuropean Radiology
Volume14
Issue number7
DOIs
Publication statusPublished - Jan 1 2004
Externally publishedYes

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Blood Vessels
Radiotherapy
Lymph Nodes
Doppler Ultrasonography
ROC Curve
Ultrasonography
Mouth Neoplasms
Drug Therapy
Therapeutics

All Science Journal Classification (ASJC) codes

  • Radiology Nuclear Medicine and imaging

Cite this

Chikui, T., Yuasa, K., Tokumori, K., Kanda, S., Kunitake, N., Nakamura, K., ... Hiraki, A. (2004). Change of sonographic findings on cervical lymph nodes before and after preoperative radiotherapy. European Radiology, 14(7), 1255-1262. https://doi.org/10.1007/s00330-003-2173-4

Change of sonographic findings on cervical lymph nodes before and after preoperative radiotherapy. / Chikui, Toru; Yuasa, Kenji; Tokumori, Kenji; Kanda, Shigenobu; Kunitake, Naonobu; Nakamura, Katsumasa; Nagata, Tetsuji; Hiraki, Akimitsu.

In: European Radiology, Vol. 14, No. 7, 01.01.2004, p. 1255-1262.

Research output: Contribution to journalArticle

Chikui, T, Yuasa, K, Tokumori, K, Kanda, S, Kunitake, N, Nakamura, K, Nagata, T & Hiraki, A 2004, 'Change of sonographic findings on cervical lymph nodes before and after preoperative radiotherapy', European Radiology, vol. 14, no. 7, pp. 1255-1262. https://doi.org/10.1007/s00330-003-2173-4
Chikui, Toru ; Yuasa, Kenji ; Tokumori, Kenji ; Kanda, Shigenobu ; Kunitake, Naonobu ; Nakamura, Katsumasa ; Nagata, Tetsuji ; Hiraki, Akimitsu. / Change of sonographic findings on cervical lymph nodes before and after preoperative radiotherapy. In: European Radiology. 2004 ; Vol. 14, No. 7. pp. 1255-1262.
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