Abstract
Changes in the thresholds for afterdischarges and the formation of kindling effect in the medial amygdala following olfactory bulbectomy were investigated in the rat with chronic electrode implants. The threshold for afterdischarges in the amygdala of the olfactory bulbectomized rat (OB rat) was significantly decreased on day 4 after olfactory bulbectomy, however, no significant difference was found between OB and sham operated rats on days 7, 14 and 21 since the threshold in the sham group was also decreased at these periods after the surgery. The formation of kindling effect was remarkably accelerated in the OB rats. In this case, the number of days required to reach the stage 1 (Racine's classification) was significantly shortened. These results suggest that the activity of the medial amygdaloid nucleus is increased following olfactory bulbectomy.
| Original language | English |
|---|---|
| Pages (from-to) | 687-692 |
| Number of pages | 6 |
| Journal | Physiology and Behavior |
| Volume | 28 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 1982 |
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All Science Journal Classification (ASJC) codes
- Experimental and Cognitive Psychology
- Behavioral Neuroscience
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Changes in amygdaloid afterdischarges and kindling effect following olfactory bulbectomy in the rat. / Watanabe, Shigenori; Nakanishi, Hiroshi; Shibata, Shigenobu; Ueki, Showa.
In: Physiology and Behavior, Vol. 28, No. 4, 04.1982, p. 687-692.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Changes in amygdaloid afterdischarges and kindling effect following olfactory bulbectomy in the rat
AU - Watanabe, Shigenori
AU - Nakanishi, Hiroshi
AU - Shibata, Shigenobu
AU - Ueki, Showa
PY - 1982/4
Y1 - 1982/4
N2 - Changes in the thresholds for afterdischarges and the formation of kindling effect in the medial amygdala following olfactory bulbectomy were investigated in the rat with chronic electrode implants. The threshold for afterdischarges in the amygdala of the olfactory bulbectomized rat (OB rat) was significantly decreased on day 4 after olfactory bulbectomy, however, no significant difference was found between OB and sham operated rats on days 7, 14 and 21 since the threshold in the sham group was also decreased at these periods after the surgery. The formation of kindling effect was remarkably accelerated in the OB rats. In this case, the number of days required to reach the stage 1 (Racine's classification) was significantly shortened. These results suggest that the activity of the medial amygdaloid nucleus is increased following olfactory bulbectomy.
AB - Changes in the thresholds for afterdischarges and the formation of kindling effect in the medial amygdala following olfactory bulbectomy were investigated in the rat with chronic electrode implants. The threshold for afterdischarges in the amygdala of the olfactory bulbectomized rat (OB rat) was significantly decreased on day 4 after olfactory bulbectomy, however, no significant difference was found between OB and sham operated rats on days 7, 14 and 21 since the threshold in the sham group was also decreased at these periods after the surgery. The formation of kindling effect was remarkably accelerated in the OB rats. In this case, the number of days required to reach the stage 1 (Racine's classification) was significantly shortened. These results suggest that the activity of the medial amygdaloid nucleus is increased following olfactory bulbectomy.
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U2 - 10.1016/0031-9384(82)90052-X
DO - 10.1016/0031-9384(82)90052-X
M3 - Article
C2 - 7200621
AN - SCOPUS:0020315506
VL - 28
SP - 687
EP - 692
JO - Physiology and Behavior
JF - Physiology and Behavior
SN - 0031-9384
IS - 4
ER -