Changes in chorioretinal blood flow velocity and cerebral blood flow after carotid endarterectomy

Hiroshi Enaida, Shinji Nagata, Atsunobu Takeda, shintaro nakao, Yasuhiro Ikeda, Tatsuro Ishibashi

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Abstract

Purpose: To investigate the changes in chorioretinal blood flow velocity and cerebral blood after carotid endarterectomy (CEA). Methods: Nine patients with moderate to severe internal carotid artery stenosis underwent CEA. Chorioretinal blood flow velocity was measured by laser speckle flowgraphy (LSFG), while cerebral blood flow (CBF) was measured by single-photon emission computed tomography (SPECT), on the affected side both before and after CEA. LSFG was evaluated in five areas to determine mean blur rate, while CBF was calculated from regional CBF and cerebrovascular reactivity (CVR), at the middle cerebral artery (MCA) region of each patient. Results: Five cases showed an increase (mean 3.49 %, range −29.82 to 35.59 %) of average chorioretinal blood flow velocity using LSFG after CEA. A particularly averaged increase in chorioretinal blood flow was observed in the macular area compared with other areas. Similarly, there was an increase in CBF at rest (mean 11.46 %, range −14.51 to 74.14 %) observed using SPECT after surgery. Improvement of CVR was confirmed in four cases. All general and visual symptoms disappeared after CEA. Severe adverse effects, including hyperperfusion syndrome, were not observed in any cases. Conclusions: LSFG may be useful for the analysis of chorioretinal blood flow changes after CEA.

Original languageEnglish
Pages (from-to)459-465
Number of pages7
JournalJapanese Journal of Ophthalmology
Volume60
Issue number6
DOIs
Publication statusPublished - Nov 1 2016

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Cerebrovascular Circulation
Blood Flow Velocity
Carotid Endarterectomy
Lasers
Single-Photon Emission-Computed Tomography
Carotid Stenosis
Regional Blood Flow
Middle Cerebral Artery

All Science Journal Classification (ASJC) codes

  • Ophthalmology

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Changes in chorioretinal blood flow velocity and cerebral blood flow after carotid endarterectomy. / Enaida, Hiroshi; Nagata, Shinji; Takeda, Atsunobu; nakao, shintaro; Ikeda, Yasuhiro; Ishibashi, Tatsuro.

In: Japanese Journal of Ophthalmology, Vol. 60, No. 6, 01.11.2016, p. 459-465.

Research output: Contribution to journalArticle

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abstract = "Purpose: To investigate the changes in chorioretinal blood flow velocity and cerebral blood after carotid endarterectomy (CEA). Methods: Nine patients with moderate to severe internal carotid artery stenosis underwent CEA. Chorioretinal blood flow velocity was measured by laser speckle flowgraphy (LSFG), while cerebral blood flow (CBF) was measured by single-photon emission computed tomography (SPECT), on the affected side both before and after CEA. LSFG was evaluated in five areas to determine mean blur rate, while CBF was calculated from regional CBF and cerebrovascular reactivity (CVR), at the middle cerebral artery (MCA) region of each patient. Results: Five cases showed an increase (mean 3.49 {\%}, range −29.82 to 35.59 {\%}) of average chorioretinal blood flow velocity using LSFG after CEA. A particularly averaged increase in chorioretinal blood flow was observed in the macular area compared with other areas. Similarly, there was an increase in CBF at rest (mean 11.46 {\%}, range −14.51 to 74.14 {\%}) observed using SPECT after surgery. Improvement of CVR was confirmed in four cases. All general and visual symptoms disappeared after CEA. Severe adverse effects, including hyperperfusion syndrome, were not observed in any cases. Conclusions: LSFG may be useful for the analysis of chorioretinal blood flow changes after CEA.",
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AU - Nagata, Shinji

AU - Takeda, Atsunobu

AU - nakao, shintaro

AU - Ikeda, Yasuhiro

AU - Ishibashi, Tatsuro

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