Changes in the cerebral and cerebellar blood flow in cerebral embolism

Masahiro Kamouchi, Yoshisuke Saku, Setsuro Ibayashi, Makoto Katsuragi, Seizo Sadoshima, Masatoshi Fujishima

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The present study was performed to elucidate the time course of the cerebral and cerebellar blood flows and the significance of SPECT for predicting the outcome in cerebral embolism. 99mTc-hexamethylpropyleneamine oxime (99mTc-HMPAO) SPECT was repeatedly performed in 60 patients with unilateral cerebral embolism. The distribution of 99mTc-HMPAO in the infarct area decreased in the acute phase, increased from 3 h to 22 days after the stroke and then gradually and eventually decreased in the chronic stage. This tendency was observed irrespective of the thrombolytic therapy. The asymmetry index (AI) in the cerebral hemisphere in the first 6 h and later than 30 days correlated significantly with activities of daily living in the chronic stage (p < 0.05). The cerebellar AI after, but not up to 14 days also correlated with the long-term outcome (p < 0.05). In conclusion, a high distribution of 99mTc-HMPAO frequently and transiently occurs in the subacute stage of cerebral embolism. The cerebral and cerebellar asymmetry of the 99mTc-HMPAO distribution is an important predictive value for the outcome; however, the timing of SPECT is critically important.

Original languageEnglish
Pages (from-to)301-307
Number of pages7
JournalCerebrovascular Diseases
Volume6
Issue number5
DOIs
Publication statusPublished - Jan 1 1996

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Cerebrovascular Circulation
Intracranial Embolism
Single-Photon Emission-Computed Tomography
Thrombolytic Therapy
Cerebrum
Activities of Daily Living
Stroke
hexamethylpropyleneamine oxime

All Science Journal Classification (ASJC) codes

  • Neurology
  • Clinical Neurology
  • Cardiology and Cardiovascular Medicine

Cite this

Kamouchi, M., Saku, Y., Ibayashi, S., Katsuragi, M., Sadoshima, S., & Fujishima, M. (1996). Changes in the cerebral and cerebellar blood flow in cerebral embolism. Cerebrovascular Diseases, 6(5), 301-307. https://doi.org/10.1159/000108042

Changes in the cerebral and cerebellar blood flow in cerebral embolism. / Kamouchi, Masahiro; Saku, Yoshisuke; Ibayashi, Setsuro; Katsuragi, Makoto; Sadoshima, Seizo; Fujishima, Masatoshi.

In: Cerebrovascular Diseases, Vol. 6, No. 5, 01.01.1996, p. 301-307.

Research output: Contribution to journalArticle

Kamouchi, M, Saku, Y, Ibayashi, S, Katsuragi, M, Sadoshima, S & Fujishima, M 1996, 'Changes in the cerebral and cerebellar blood flow in cerebral embolism', Cerebrovascular Diseases, vol. 6, no. 5, pp. 301-307. https://doi.org/10.1159/000108042
Kamouchi, Masahiro ; Saku, Yoshisuke ; Ibayashi, Setsuro ; Katsuragi, Makoto ; Sadoshima, Seizo ; Fujishima, Masatoshi. / Changes in the cerebral and cerebellar blood flow in cerebral embolism. In: Cerebrovascular Diseases. 1996 ; Vol. 6, No. 5. pp. 301-307.
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