Changes in the molecular types of connectin and nebulin during development of chicken skeletal muscle

Akihito Hattori, Tatsuo Ishii, Ryuichi Tatsumi, Koui Takahashi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Changes in the molecular types of connectin and nebulin during development of chicken breast and leg muscles were determined by an improved SDS-polyacrylamide gel electrophoresis (PAGE) using 2% polyacrylamide slab gel. The adult leg-type α-connectin (αL-connectin) and nebulin (L-nebulin) appeared in embryonic breast muscle, and changed into the adult breast-type ones (αB-connectin, B-nebulin) specific for adult breast muscle after hatching. In leg muscle, αL-connectin and L-nebulin appeared in an embryonic stage, and remained unchanged in molecular types throughout the entire process of development. α-Connectin and nebulin seemed to be regulated by a similar mechanism during development. On the other hand, β-connectin appeared in an earlier stage of development of the embryonic breast muscle, independently of a-connectin.

Original languageEnglish
Pages (from-to)179-184
Number of pages6
JournalBBA - General Subjects
Volume1244
Issue number1
DOIs
Publication statusPublished - May 11 1995

All Science Journal Classification (ASJC) codes

  • Biophysics
  • Biochemistry
  • Molecular Biology

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