Characteristic Cytological Features of Cervical Clear Cell Adenocarcinoma: A Report of 4 Cases: A Case Report

Kenzo Sonoda, Miwako Nogami, Masaki Naka, Fumihiko Ookubo, Hiroaki Kobayashi, Hideaki Yahata, Okugawa Kaoru, Kaneki Eisuke, Yoshinao Oda, Kiyoko Kato

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Abstract

We experienced 5 cases of clear cell adenocarcinoma (CCAC) of the cervix in the 10-year period from 2003 to 2012. Because a specimen from one of the cases was poorly preserved, we analyzed cytological features of the 4 remaining cases. Characteristic large, pale-staining atypical cells with prominent, round nuclei were seen in all cases. Additionally, a hobnail appearance and basement membrane-like substance were detected in 3 cases, and a mirror ball cluster-like morphology was found in 1 case. Cervical CCAC has been reported to be difficult to diagnose by cytology; however, we were able to diagnose these 4 cases by recognizing several characteristic cytological features.
Original languageEnglish
Pages (from-to)1-4
JournalJournal of Cytology & Histology
Publication statusPublished - Nov 22 2013

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Clear Cell Adenocarcinoma
Basement Membrane
Cervix Uteri
Cell Biology
Staining and Labeling

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Characteristic Cytological Features of Cervical Clear Cell Adenocarcinoma: A Report of 4 Cases : A Case Report. / Sonoda, Kenzo; Nogami, Miwako; Naka, Masaki; Ookubo, Fumihiko; Kobayashi, Hiroaki; Yahata, Hideaki; Kaoru, Okugawa; Eisuke, Kaneki; Oda, Yoshinao; Kato, Kiyoko.

In: Journal of Cytology & Histology, 22.11.2013, p. 1-4.

Research output: Contribution to journalArticle

Sonoda, Kenzo ; Nogami, Miwako ; Naka, Masaki ; Ookubo, Fumihiko ; Kobayashi, Hiroaki ; Yahata, Hideaki ; Kaoru, Okugawa ; Eisuke, Kaneki ; Oda, Yoshinao ; Kato, Kiyoko. / Characteristic Cytological Features of Cervical Clear Cell Adenocarcinoma: A Report of 4 Cases : A Case Report. In: Journal of Cytology & Histology. 2013 ; pp. 1-4.
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AU - Yahata, Hideaki

AU - Kaoru, Okugawa

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AU - Oda, Yoshinao

AU - Kato, Kiyoko

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