Characteristic findings of hepatocellular carcinoma: An evaluation with comparative study of US, CT, and MRI

Hiroshi Honda, Hideo Onitsuka, Junji Murakami, Kuniyuki Kaneko, Sadayuki Murayama, Eisuke Adachi, Takashi Kanematsu, Keizou Sugimachi, Kouji Masuda

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    49 Citations (Scopus)

    Abstract

    The sensitivity, specificity, and accuracy of ultrasonography (US), dynamic incremented computed tomography (CT) with delayed phase imaging, and magnetic resonance imaging (MRI) with or without Gd-DTPA were studied for detecting the characteristic appearances of hepatocellular carcinomas (HCC): fibrous capsules, fibrous septa, and mosaic appearances. Results were prospectively evaluated in 30 patients who subsequently underwent hepatic lobectomies or segmentectomies. Pathologic evaluations of the resected liver specimens demonstrated fibrous capsules in 20 tumors (66.7%), fibrous septa in 13 tumors (43.3%), and mosaic appearances in 19 tumors (63.3%). The accuracies for fibrous capsules were 71.4% (20 of 28) for US, 81.5% (22 of 27) for CT, and 92.3% (24 of 26) for MRI. The accuracies for fibrous septa were 57.1% (16 of 28) for US, 59.3% (16 of 27) for CT, and 73.1% (19 of 26) for MRI. The accuracies for mosaic appearances were 71.4% (20 of 28) for US, 51.9% (14 of 27) for CT, and 69.2% (18 of 26) for MRI. Gd-DTPA administrated MRI showed higher accuracies than did conventional MRI for all manifestations. In conclusion, the fibrous capsules of HCCs were readily detected by CT and MRI. Gd-DTPA administration demonstrated an advantage in clarifying fibrous capsules, as well as fibrous septa and mosaic appearances.

    Original languageEnglish
    Pages (from-to)245-249
    Number of pages5
    JournalGastrointestinal Radiology
    Volume17
    Issue number1
    DOIs
    Publication statusPublished - Dec 1 1992

    All Science Journal Classification (ASJC) codes

    • Radiology Nuclear Medicine and imaging
    • Gastroenterology

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