Characteristics of differentiation of osteoclast cells irradiated with active species in atmospheric oxygen plasma

Nobuya Hayashi, Yuki Inoue, Yukari Kyumoto, Toshio Kukita

Research output: Contribution to journalArticle

Abstract

Variations in osteoclast cell number are observed when osteoclast precursor cells are irradiated with atmospheric dielectric barrier discharge plasma. Active species generated by the oxygen plasma control the differentiation function of the osteoclast precursor cells. Long-lifetime active species such as H2O2 and NO x - dissolved in the culture medium decrease the osteoclast number due to the inactivation of the differentiation function of the osteoclast precursor cells. When short-lifetime active species such as O∗ and OH∗ make contact with the osteoclast precursor cells directly, the osteoclast number tends to increase. Short-lifetime active species induce the enhancement of the gene expression of NFATc1.

Original languageEnglish
Article numberSJJF02
JournalJapanese journal of applied physics
Volume59
Issue numberSJ
DOIs
Publication statusPublished - Jun 1 2020

All Science Journal Classification (ASJC) codes

  • Engineering(all)
  • Physics and Astronomy(all)

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