Characteristics of lumbar scoliosis in patients with rheumatoid arthritis

Masanobu Ohishi, Hisaaki Miyahara, Masakazu Kondo, Yasuharu Nakashima, Kazumasa Terada, Yukio Esaki, Nobuo Kobara, Katsumi Harimaya, Yoshihiro Matsumoto, Yukihide Iwamoto

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Background: Although a substantial percentage of patients with rheumatoid arthritis (RA) experience low back pain, the characteristics of lumbar spine pathology in RA patients has been poorly investigated. In our institutions, lumbar spine radiographs indicated scoliosis in 26 patients. The present study aimed to clarify the characteristics of lumbar scoliosis in RA patients. Methods: This is a retrospective study of 26 RA patients with lumbar scoliosis. Patient characteristics such as disease duration, disease stage and class according to Steinbrocker's classification, and medication for RA and osteoporosis were reviewed. Radiologic evaluation of scoliosis was performed at two different time points by measuring Cobb angles. The progression of scoliosis per year was calculated by dividing the change in Cobb angles by the number of years. Apical vertebral rotation, lateral listhesis, and the level of the intercrestal line at the first observation were also measured. The correlation between different factors and changes in the Cobb angles per year was analyzed. Results: Majority of the patients had a long disease duration and were classified as stage 3 or 4 according to Steinbrocker's classification. During the observation period, most patients were treated with glucocorticoids. Unlike the previous studies on degenerative scoliosis, apical vertebral rotation, lateral listhesis, and the level of the intercrestal line at initial observation were not significantly related to the progression of scoliosis. Initial Cobb angles were inversely related to the progression of scoliosis. Patients who were treated with bisphosphonates showed slower progression of scoliosis. Conclusions: Our results indicate that the characteristics of lumbar scoliosis in RA patients differ from those of degenerative lumbar scoliosis. Bone fragility due to the long disease duration, poor control of disease activity, and osteoporosis is possibly related to its progression.

Original languageEnglish
Article number30
JournalJournal of Orthopaedic Surgery and Research
Volume9
Issue number1
DOIs
Publication statusPublished - Apr 26 2014

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Scoliosis
Rheumatoid Arthritis
Observation
Osteoporosis
Spine
Diphosphonates
Low Back Pain
Glucocorticoids
Retrospective Studies
Pathology
Bone and Bones

All Science Journal Classification (ASJC) codes

  • Surgery
  • Orthopedics and Sports Medicine

Cite this

Characteristics of lumbar scoliosis in patients with rheumatoid arthritis. / Ohishi, Masanobu; Miyahara, Hisaaki; Kondo, Masakazu; Nakashima, Yasuharu; Terada, Kazumasa; Esaki, Yukio; Kobara, Nobuo; Harimaya, Katsumi; Matsumoto, Yoshihiro; Iwamoto, Yukihide.

In: Journal of Orthopaedic Surgery and Research, Vol. 9, No. 1, 30, 26.04.2014.

Research output: Contribution to journalArticle

Ohishi, Masanobu ; Miyahara, Hisaaki ; Kondo, Masakazu ; Nakashima, Yasuharu ; Terada, Kazumasa ; Esaki, Yukio ; Kobara, Nobuo ; Harimaya, Katsumi ; Matsumoto, Yoshihiro ; Iwamoto, Yukihide. / Characteristics of lumbar scoliosis in patients with rheumatoid arthritis. In: Journal of Orthopaedic Surgery and Research. 2014 ; Vol. 9, No. 1.
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