Characterization of superparamagnetic Fe3 O4 nanoparticles by fluxgate magnetorelaxometry for use in biomedical applications

F. Ludwig, E. Heim, M. Schilling, K. Enpuku

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Abstract

We have investigated the magnetorelaxometry (MRX) of various Fe3 O4 nanoparticle suspensions utilizing a differential fluxgate setup. To estimate the distribution of the hydrodynamic size of the magnetic nanoparticles (MNPs) with organic shell, the cluster moment superposition model is applied. On a sample series of MNPs from the same batch diluted in water-glycerine mixtures of varying viscosity, it is demonstrated that the model is suited for the estimation of the distribution of the hydrodynamic size of MNPs and clusters. Since a MRX measurement lasts only a few seconds, it is also highly suited to study the aggregation kinetics. This is demonstrated on MNPs with silica shell suspended in 5% phosphate-buffered saline solution.

Original languageEnglish
Article number07A314
JournalJournal of Applied Physics
Volume103
Issue number7
DOIs
Publication statusPublished - Apr 21 2008

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All Science Journal Classification (ASJC) codes

  • Physics and Astronomy(all)

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