TY - GEN
T1 - Chick embryo cultured in a cubic eggshell as a promising animal model
AU - Huang, Wenjing
AU - Arai, Fumihito
AU - Kawahara, Tomohiro
N1 - Publisher Copyright:
© 2014 IEEE.
PY - 2015/1/9
Y1 - 2015/1/9
N2 - We have proposed a novel cubic (artificial) eggshell containing a chick embryo. Since the posture of the eggshell can be changed freely and the manipulation of the chick embryo is possible, the developed cubic eggshell with a chick embryo is a good model for microsurgery training. In this study, we further demonstrate the promising use of the eggshell. First, the viability of the chick embryo in the cubic eggshell is confirmed through basic experiments. Second, we show that the development of embryo tissues and circulatory system can be easily observed. Third, blood vessel formation can be spatially controlled by using patterned side membranes, which have localized oxygen-permeable properties. Together with the previous results about the manipulation of the embryo, these results suggest that chick embryos cultured in the developed cubic eggshell can be used as a promising animal model for biomedical research such as angiogenesis and drug delivery testing.
AB - We have proposed a novel cubic (artificial) eggshell containing a chick embryo. Since the posture of the eggshell can be changed freely and the manipulation of the chick embryo is possible, the developed cubic eggshell with a chick embryo is a good model for microsurgery training. In this study, we further demonstrate the promising use of the eggshell. First, the viability of the chick embryo in the cubic eggshell is confirmed through basic experiments. Second, we show that the development of embryo tissues and circulatory system can be easily observed. Third, blood vessel formation can be spatially controlled by using patterned side membranes, which have localized oxygen-permeable properties. Together with the previous results about the manipulation of the embryo, these results suggest that chick embryos cultured in the developed cubic eggshell can be used as a promising animal model for biomedical research such as angiogenesis and drug delivery testing.
UR - http://www.scopus.com/inward/record.url?scp=84922168114&partnerID=8YFLogxK
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U2 - 10.1109/MHS.2014.7006077
DO - 10.1109/MHS.2014.7006077
M3 - Conference contribution
AN - SCOPUS:84922168114
T3 - 2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014
BT - 2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014
Y2 - 10 November 2014 through 12 November 2014
ER -