Chick embryo cultured in a cubic eggshell as a promising animal model

Wenjing Huang, Fumihito Arai, Tomohiro Kawahara

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have proposed a novel cubic (artificial) eggshell containing a chick embryo. Since the posture of the eggshell can be changed freely and the manipulation of the chick embryo is possible, the developed cubic eggshell with a chick embryo is a good model for microsurgery training. In this study, we further demonstrate the promising use of the eggshell. First, the viability of the chick embryo in the cubic eggshell is confirmed through basic experiments. Second, we show that the development of embryo tissues and circulatory system can be easily observed. Third, blood vessel formation can be spatially controlled by using patterned side membranes, which have localized oxygen-permeable properties. Together with the previous results about the manipulation of the embryo, these results suggest that chick embryos cultured in the developed cubic eggshell can be used as a promising animal model for biomedical research such as angiogenesis and drug delivery testing.

Original languageEnglish
Title of host publication2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781479966790
DOIs
Publication statusPublished - Jan 9 2015
Externally publishedYes
Event2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014 - Nagoya, Japan
Duration: Nov 10 2014Nov 12 2014

Publication series

Name2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014

Other

Other2014 International Symposium on Micro-NanoMechatronics and Human Science, MHS 2014
CountryJapan
CityNagoya
Period11/10/1411/12/14

All Science Journal Classification (ASJC) codes

  • Electrical and Electronic Engineering
  • Mechanical Engineering

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