Chiral ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification to 2-acyl tetrahydrofurans

Muhammet Uyanik; Hiroki Hayashi; Hirokazu Iwata; Kazuaki Ishihara

doi:10.1246/cl.160004

Chiral ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification to 2-acyl tetrahydrofurans

Muhammet Uyanik, Hiroki Hayashi, Hirokazu Iwata, Kazuaki Ishihara

Research output: Contribution to journal › Article

16 Citations (Scopus)

Abstract

2-Acyl tetrahydrofuran is a fundamental structure in natural products and pharmaceuticals. We achieved chiral quaternary ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification of δ-hydroxyketone derivatives. The corresponding 2-acyl tetrahydrofurans were obtained in high chemical yield with high enantioselectivity.

Original language	English
Pages (from-to)	353-355
Number of pages	3
Journal	Chemistry Letters
Volume	45
Issue number	3
DOIs	https://doi.org/10.1246/cl.160004
Publication status	Published - Jan 1 2016
Externally published	Yes

Fingerprint

Furans

Enantioselectivity

Biological Products

Ammonium Compounds

Salts

Derivatives

Pharmaceutical Preparations

tetrahydrofuran

hypoiodous acid

All Science Journal Classification (ASJC) codes

Chemistry(all)

Cite this

Uyanik, M., Hayashi, H., Iwata, H., & Ishihara, K. (2016). Chiral ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification to 2-acyl tetrahydrofurans. Chemistry Letters, 45(3), 353-355. https://doi.org/10.1246/cl.160004

Chiral ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification to 2-acyl tetrahydrofurans. / Uyanik, Muhammet; Hayashi, Hiroki; Iwata, Hirokazu; Ishihara, Kazuaki.

In: Chemistry Letters, Vol. 45, No. 3, 01.01.2016, p. 353-355.

Research output: Contribution to journal › Article

Uyanik, M, Hayashi, H, Iwata, H & Ishihara, K 2016, 'Chiral ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification to 2-acyl tetrahydrofurans', Chemistry Letters, vol. 45, no. 3, pp. 353-355. https://doi.org/10.1246/cl.160004

Uyanik M, Hayashi H, Iwata H, Ishihara K. Chiral ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification to 2-acyl tetrahydrofurans. Chemistry Letters. 2016 Jan 1;45(3):353-355. https://doi.org/10.1246/cl.160004

Uyanik, Muhammet ; Hayashi, Hiroki ; Iwata, Hirokazu ; Ishihara, Kazuaki. / Chiral ammonium hypoiodite salt-catalyzed enantioselective oxidative cycloetherification to 2-acyl tetrahydrofurans. In: Chemistry Letters. 2016 ; Vol. 45, No. 3. pp. 353-355.

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Access to Document

10.1246/cl.160004