Chiral dienolate chemistry in remote asymmetric induction: The asymmetric aldol/oxy-Cope strategy for asymmetric synthesis of γ,δ-dichiral α,β-unsaturated acid derivatives

Katsuhiko Tomooka, Atsushi Nagasawa, Shih Yi Wei, Takeshi Nakai

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

The asymmetric aldol reaction of the boron dienolate derived from chiral α,β- or β,γ-unsaturated imide followed by the siloxy-Cope rearrangement is shown to provide the γ,δ-anti- or -syn -α,β-unsaturated imide as the main product. Copyright (C) 1996 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)8899-8900
Number of pages2
JournalTetrahedron Letters
Volume37
Issue number49
DOIs
Publication statusPublished - Dec 2 1996
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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