Cholecystokinin is not a major regulator in the digestive system in the chicken

S. Satoh, Mitsuhiro Furuse, Y. H. Choi, J. Okumura

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

To find out whether physiological concentrations of cholecystokinin (CCK), a gastrointestinal hormone in mammals, are also active in chickens, the pancreatic amylase secretory response to CCK-8 was investigated in vitro. Rat pancreatic acini responded to the physiological concentration of CCK-8, but in chickens amylase release was induced at a concentration of CCK-8 1000 times higher than that observed in rats. In another experiment, biliary flow was tested with several doses of CCK-8. The bile flow was stimulated in a dose-dependent fashion, but a significant enhancement was not obtained at a concentration of 0.5 μg CCK-8/kg body weight, which was considerably higher than physiological ones. It is concluded that endogeneous CCK does not have an important role in the digestive system in the chicken.

Original languageEnglish
Pages (from-to)812-814
Number of pages3
JournalExperientia
Volume50
Issue number9
DOIs
Publication statusPublished - Sep 1 1994
Externally publishedYes

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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