Chronic hypertrophic cranial pachymeningitis associated with HTLV-I infection

Y. Kawano, Jun-Ichi Kira

Research output: Contribution to journalArticle

47 Citations (Scopus)

Abstract

Two patients presenting with recurrent multiple cranial neuropathy showed diffuse thickening and gadolinium enhancement of the dura mater on brain MRI. Both had anti-HTLV-I antibodies in serum. A quantitative polymerase chain reaction study ofthe peripheral blood disclosed that the HTLV-I proviral DNA loads increased considerably in one case and moderately in the other. Both showed a spontaneous proliferation of peripheral blood lymphocytes as well as an increase in helper/inducer T cells. Neither had any other underlying infections or autoimmune diseases. Thus it is possible that hypertrophic pachymeningitis developed as a result of multiorgan involvement of HTLV-I infection in these patients.

Original languageEnglish
Pages (from-to)435-437
Number of pages3
JournalJournal of Neurology, Neurosurgery and Psychiatry
Volume59
Issue number4
DOIs
Publication statusPublished - Jan 1 1995

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HTLV-I Infections
Meningitis
HTLV-I Antibodies
Cranial Nerve Diseases
Dura Mater
Human T-lymphotropic virus 1
Gadolinium
Helper-Inducer T-Lymphocytes
Autoimmune Diseases
Lymphocytes
Polymerase Chain Reaction
DNA
Brain
Infection
Serum

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology
  • Psychiatry and Mental health

Cite this

Chronic hypertrophic cranial pachymeningitis associated with HTLV-I infection. / Kawano, Y.; Kira, Jun-Ichi.

In: Journal of Neurology, Neurosurgery and Psychiatry, Vol. 59, No. 4, 01.01.1995, p. 435-437.

Research output: Contribution to journalArticle

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