Abstract
Cistanche salsa (C.A. Meyer) G. Beck, Orobanchaceae is a parasitic plant that is used as an oriental medicinal tonic in Japan. In this study, we show that the extract prepared from C. salsa enhanced antibody production in human lymph node lymphocytes (LNL). The production of IgM and IgG was shown to be enhanced 5-fold. The extract also induced interleukin-6 receptor (IL-6R) expression on surface immunoglobulin positive B cells in LNL. These results raise a possibility that the antibody production enhanced by the C. salsa extract may be related to the involvement of IL-6R expression in B cell activation.
| Original language | English |
|---|---|
| Pages (from-to) | 341-348 |
| Number of pages | 8 |
| Journal | Pharmacologyonline |
| Volume | 2 |
| Publication status | Published - Oct 2 2008 |
All Science Journal Classification (ASJC) codes
- Pharmacology
- Drug Discovery
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Maruyama, S., Hashizume, S., Tanji, T., Yamada, K., & Tachibana, H. (2008). Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes. Pharmacologyonline, 2, 341-348.