Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes

Shinjiro Maruyama; Shuichi Hashizume; Touji Tanji; Koji Yamada; Hirofumi Tachibana

Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes

Shinjiro Maruyama, Shuichi Hashizume, Touji Tanji, Koji Yamada, Hirofumi Tachibana

Food Science and Biotechnology

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

Cistanche salsa (C.A. Meyer) G. Beck, Orobanchaceae is a parasitic plant that is used as an oriental medicinal tonic in Japan. In this study, we show that the extract prepared from C. salsa enhanced antibody production in human lymph node lymphocytes (LNL). The production of IgM and IgG was shown to be enhanced 5-fold. The extract also induced interleukin-6 receptor (IL-6R) expression on surface immunoglobulin positive B cells in LNL. These results raise a possibility that the antibody production enhanced by the C. salsa extract may be related to the involvement of IL-6R expression in B cell activation.

Original language	English
Pages (from-to)	341-348
Number of pages	8
Journal	Pharmacologyonline
Volume	2
Publication status	Published - Oct 2 2008

All Science Journal Classification (ASJC) codes

Pharmacology
Drug Discovery

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title = "Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes",

abstract = "Cistanche salsa (C.A. Meyer) G. Beck, Orobanchaceae is a parasitic plant that is used as an oriental medicinal tonic in Japan. In this study, we show that the extract prepared from C. salsa enhanced antibody production in human lymph node lymphocytes (LNL). The production of IgM and IgG was shown to be enhanced 5-fold. The extract also induced interleukin-6 receptor (IL-6R) expression on surface immunoglobulin positive B cells in LNL. These results raise a possibility that the antibody production enhanced by the C. salsa extract may be related to the involvement of IL-6R expression in B cell activation.",

author = "Shinjiro Maruyama and Shuichi Hashizume and Touji Tanji and Koji Yamada and Hirofumi Tachibana",

year = "2008",

month = oct,

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language = "English",

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T1 - Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes

AU - Maruyama, Shinjiro

AU - Hashizume, Shuichi

AU - Tanji, Touji

AU - Yamada, Koji

AU - Tachibana, Hirofumi

PY - 2008/10/2

Y1 - 2008/10/2

N2 - Cistanche salsa (C.A. Meyer) G. Beck, Orobanchaceae is a parasitic plant that is used as an oriental medicinal tonic in Japan. In this study, we show that the extract prepared from C. salsa enhanced antibody production in human lymph node lymphocytes (LNL). The production of IgM and IgG was shown to be enhanced 5-fold. The extract also induced interleukin-6 receptor (IL-6R) expression on surface immunoglobulin positive B cells in LNL. These results raise a possibility that the antibody production enhanced by the C. salsa extract may be related to the involvement of IL-6R expression in B cell activation.

AB - Cistanche salsa (C.A. Meyer) G. Beck, Orobanchaceae is a parasitic plant that is used as an oriental medicinal tonic in Japan. In this study, we show that the extract prepared from C. salsa enhanced antibody production in human lymph node lymphocytes (LNL). The production of IgM and IgG was shown to be enhanced 5-fold. The extract also induced interleukin-6 receptor (IL-6R) expression on surface immunoglobulin positive B cells in LNL. These results raise a possibility that the antibody production enhanced by the C. salsa extract may be related to the involvement of IL-6R expression in B cell activation.

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EP - 348

JO - Pharmacologyonline

JF - Pharmacologyonline

SN - 1827-8620

ER -

Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes

Abstract

All Science Journal Classification (ASJC) codes

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