Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes

Shinjiro Maruyama, Shuichi Hashizume, Touji Tanji, Koji Yamada, Hirofumi Tachibana

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

Cistanche salsa (C.A. Meyer) G. Beck, Orobanchaceae is a parasitic plant that is used as an oriental medicinal tonic in Japan. In this study, we show that the extract prepared from C. salsa enhanced antibody production in human lymph node lymphocytes (LNL). The production of IgM and IgG was shown to be enhanced 5-fold. The extract also induced interleukin-6 receptor (IL-6R) expression on surface immunoglobulin positive B cells in LNL. These results raise a possibility that the antibody production enhanced by the C. salsa extract may be related to the involvement of IL-6R expression in B cell activation.

Original languageEnglish
Pages (from-to)341-348
Number of pages8
JournalPharmacologyonline
Volume2
Publication statusPublished - Oct 2 2008

All Science Journal Classification (ASJC) codes

  • Pharmacology
  • Drug Discovery

Fingerprint Dive into the research topics of 'Cistanche salsa extract enhanced antibody production in human lymph node lymphocytes'. Together they form a unique fingerprint.

  • Cite this