Clinical application for intra-coronary nanodds devices

Kaku Nakano, Kensuke Egashira, Takeo Yufu

    Research output: Contribution to journalArticlepeer-review

    Abstract

    Drug eluting stent on the market at present is feared about serious side effects after use (Acute coronary syndrome caused by delayed thrombosis). It is suggested that delayed thrombosis comes from inflammatory reaction, fibrin deposition, and delayed re-endothelialization. We have already succeeded in the development of stent platform that has the function of Nano DDS using electro-deposition coating technology. In this review, we summarize the results of Pulse-Wave Infusion Catheter and statin nanoparticle eluting stent acquiring Proof of Concept by the porcine coronary-arteries models, with describing the outline of stent platform that has the function of Nano DDS.

    Original languageEnglish
    Pages (from-to)275-282
    Number of pages8
    JournalDrug Delivery System
    Volume27
    Issue number4
    DOIs
    Publication statusPublished - 2012

    All Science Journal Classification (ASJC) codes

    • Pharmaceutical Science

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