Clinical application for intra-coronary nanodds devices

Kaku Nakano, Kensuke Egashira, Takeo Yufu

Research output: Contribution to journalArticle

Abstract

Drug eluting stent on the market at present is feared about serious side effects after use (Acute coronary syndrome caused by delayed thrombosis). It is suggested that delayed thrombosis comes from inflammatory reaction, fibrin deposition, and delayed re-endothelialization. We have already succeeded in the development of stent platform that has the function of Nano DDS using electro-deposition coating technology. In this review, we summarize the results of Pulse-Wave Infusion Catheter and statin nanoparticle eluting stent acquiring Proof of Concept by the porcine coronary-arteries models, with describing the outline of stent platform that has the function of Nano DDS.

Original languageEnglish
Pages (from-to)275-282
Number of pages8
JournalDrug Delivery System
Volume27
Issue number4
DOIs
Publication statusPublished - Jan 1 2012

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Stents
Equipment and Supplies
Thrombosis
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Drug-Eluting Stents
Acute Coronary Syndrome
Fibrin
Nanoparticles
Pulse
Coronary Vessels
Swine
Catheters
Technology

All Science Journal Classification (ASJC) codes

  • Pharmaceutical Science

Cite this

Clinical application for intra-coronary nanodds devices. / Nakano, Kaku; Egashira, Kensuke; Yufu, Takeo.

In: Drug Delivery System, Vol. 27, No. 4, 01.01.2012, p. 275-282.

Research output: Contribution to journalArticle

Nakano, Kaku ; Egashira, Kensuke ; Yufu, Takeo. / Clinical application for intra-coronary nanodds devices. In: Drug Delivery System. 2012 ; Vol. 27, No. 4. pp. 275-282.
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