Clinical characteristics of lower bowel perforation with chronic renal failure

Takaaki Masuda, Yasunori Iso, Satoru Funahashi, Masahiro Tateishi, Ichiro Shima, Akinori Kido, Tadanobu Gohya, Hidetaka Masuda

Research output: Contribution to journalArticle

Abstract

Background/Aims: This study was conducted to evaluate the clinical characteristics of lower bowel perforation (LBP) with chronic renal failure (CRF). Methodology: In 58 patients with LBP, clinical variables, such as findings of clinical examinations, operative findings, and results of laboratory blood tests were examined as possible prognostic factors for in-hospital death, and compared between CRF and non-CRF groups. Results: Of the 58 patients, 21 died during hospitalization (mortality rate, 36.2%). The mortality rate of patients with CRF was 54.2%. In the patients with LBP, the following variables were significantly correlated with in-hospital death (p<0.05): hypotension, CRF, fecal peritonitis, and low white blood cell (WBC) count, and low albumin and base excess (BE) levels. The odds ratios of in-hospital death were highest for a WBC count of 9000/mm3 and a BE of -3mEq/L. Between the CRF and non-CRF groups, significant differences in the rates of age <70 years, fecal peritonitis, in-hospital death, and low WBC count and BE were found (p<0.05). Conclusions: We identified prognostic factors of LBP and demonstrated the clinical characteristics of LBP with CRF. These results indicate that patients who have LBP with CRF tend to have immediate sepsis and a poor prognosis.

Original languageEnglish
Pages (from-to)1640-1644
Number of pages5
JournalHepato-Gastroenterology
Volume55
Issue number86-87
Publication statusPublished - Sep 2008
Externally publishedYes

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Chronic Kidney Failure
Leukocyte Count
Peritonitis
Renal Insufficiency
Mortality
Hematologic Tests
Hypotension
Albumins
Sepsis
Hospitalization
Odds Ratio

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology

Cite this

Masuda, T., Iso, Y., Funahashi, S., Tateishi, M., Shima, I., Kido, A., ... Masuda, H. (2008). Clinical characteristics of lower bowel perforation with chronic renal failure. Hepato-Gastroenterology, 55(86-87), 1640-1644.

Clinical characteristics of lower bowel perforation with chronic renal failure. / Masuda, Takaaki; Iso, Yasunori; Funahashi, Satoru; Tateishi, Masahiro; Shima, Ichiro; Kido, Akinori; Gohya, Tadanobu; Masuda, Hidetaka.

In: Hepato-Gastroenterology, Vol. 55, No. 86-87, 09.2008, p. 1640-1644.

Research output: Contribution to journalArticle

Masuda, T, Iso, Y, Funahashi, S, Tateishi, M, Shima, I, Kido, A, Gohya, T & Masuda, H 2008, 'Clinical characteristics of lower bowel perforation with chronic renal failure', Hepato-Gastroenterology, vol. 55, no. 86-87, pp. 1640-1644.
Masuda T, Iso Y, Funahashi S, Tateishi M, Shima I, Kido A et al. Clinical characteristics of lower bowel perforation with chronic renal failure. Hepato-Gastroenterology. 2008 Sep;55(86-87):1640-1644.
Masuda, Takaaki ; Iso, Yasunori ; Funahashi, Satoru ; Tateishi, Masahiro ; Shima, Ichiro ; Kido, Akinori ; Gohya, Tadanobu ; Masuda, Hidetaka. / Clinical characteristics of lower bowel perforation with chronic renal failure. In: Hepato-Gastroenterology. 2008 ; Vol. 55, No. 86-87. pp. 1640-1644.
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