Abstract
Background/Aims: This study was conducted to evaluate the clinical characteristics of lower bowel perforation (LBP) with chronic renal failure (CRF). Methodology: In 58 patients with LBP, clinical variables, such as findings of clinical examinations, operative findings, and results of laboratory blood tests were examined as possible prognostic factors for in-hospital death, and compared between CRF and non-CRF groups. Results: Of the 58 patients, 21 died during hospitalization (mortality rate, 36.2%). The mortality rate of patients with CRF was 54.2%. In the patients with LBP, the following variables were significantly correlated with in-hospital death (p<0.05): hypotension, CRF, fecal peritonitis, and low white blood cell (WBC) count, and low albumin and base excess (BE) levels. The odds ratios of in-hospital death were highest for a WBC count of 9000/mm3 and a BE of -3mEq/L. Between the CRF and non-CRF groups, significant differences in the rates of age <70 years, fecal peritonitis, in-hospital death, and low WBC count and BE were found (p<0.05). Conclusions: We identified prognostic factors of LBP and demonstrated the clinical characteristics of LBP with CRF. These results indicate that patients who have LBP with CRF tend to have immediate sepsis and a poor prognosis.
| Original language | English |
|---|---|
| Pages (from-to) | 1640-1644 |
| Number of pages | 5 |
| Journal | Hepato-Gastroenterology |
| Volume | 55 |
| Issue number | 86-87 |
| Publication status | Published - Sep 2008 |
| Externally published | Yes |
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All Science Journal Classification (ASJC) codes
- Hepatology
- Gastroenterology
Cite this
Clinical characteristics of lower bowel perforation with chronic renal failure. / Masuda, Takaaki; Iso, Yasunori; Funahashi, Satoru; Tateishi, Masahiro; Shima, Ichiro; Kido, Akinori; Gohya, Tadanobu; Masuda, Hidetaka.
In: Hepato-Gastroenterology, Vol. 55, No. 86-87, 09.2008, p. 1640-1644.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical characteristics of lower bowel perforation with chronic renal failure
AU - Masuda, Takaaki
AU - Iso, Yasunori
AU - Funahashi, Satoru
AU - Tateishi, Masahiro
AU - Shima, Ichiro
AU - Kido, Akinori
AU - Gohya, Tadanobu
AU - Masuda, Hidetaka
PY - 2008/9
Y1 - 2008/9
N2 - Background/Aims: This study was conducted to evaluate the clinical characteristics of lower bowel perforation (LBP) with chronic renal failure (CRF). Methodology: In 58 patients with LBP, clinical variables, such as findings of clinical examinations, operative findings, and results of laboratory blood tests were examined as possible prognostic factors for in-hospital death, and compared between CRF and non-CRF groups. Results: Of the 58 patients, 21 died during hospitalization (mortality rate, 36.2%). The mortality rate of patients with CRF was 54.2%. In the patients with LBP, the following variables were significantly correlated with in-hospital death (p<0.05): hypotension, CRF, fecal peritonitis, and low white blood cell (WBC) count, and low albumin and base excess (BE) levels. The odds ratios of in-hospital death were highest for a WBC count of 9000/mm3 and a BE of -3mEq/L. Between the CRF and non-CRF groups, significant differences in the rates of age <70 years, fecal peritonitis, in-hospital death, and low WBC count and BE were found (p<0.05). Conclusions: We identified prognostic factors of LBP and demonstrated the clinical characteristics of LBP with CRF. These results indicate that patients who have LBP with CRF tend to have immediate sepsis and a poor prognosis.
AB - Background/Aims: This study was conducted to evaluate the clinical characteristics of lower bowel perforation (LBP) with chronic renal failure (CRF). Methodology: In 58 patients with LBP, clinical variables, such as findings of clinical examinations, operative findings, and results of laboratory blood tests were examined as possible prognostic factors for in-hospital death, and compared between CRF and non-CRF groups. Results: Of the 58 patients, 21 died during hospitalization (mortality rate, 36.2%). The mortality rate of patients with CRF was 54.2%. In the patients with LBP, the following variables were significantly correlated with in-hospital death (p<0.05): hypotension, CRF, fecal peritonitis, and low white blood cell (WBC) count, and low albumin and base excess (BE) levels. The odds ratios of in-hospital death were highest for a WBC count of 9000/mm3 and a BE of -3mEq/L. Between the CRF and non-CRF groups, significant differences in the rates of age <70 years, fecal peritonitis, in-hospital death, and low WBC count and BE were found (p<0.05). Conclusions: We identified prognostic factors of LBP and demonstrated the clinical characteristics of LBP with CRF. These results indicate that patients who have LBP with CRF tend to have immediate sepsis and a poor prognosis.
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M3 - Article
C2 - 19102359
AN - SCOPUS:57049135208
VL - 55
SP - 1640
EP - 1644
JO - Acta hepato-splenologica
JF - Acta hepato-splenologica
SN - 0172-6390
IS - 86-87
ER -