Abstract
Acute esophageal mucosal lesions (AEMLs) are categorized into black esophagitis (type B) and non-black esophagitis (type NB) on endoscopy. To clarify the distinct pathophysiology, we compared the clinical features and hematological findings at onset among 17 patients with type B esophagitis and 6 patients with type NB esophagitis. In type B esophagitis, time to endoscopy after onset was significantly shorter, and blood levels of lactate, urea nitrogen, creatinine, and glucose were higher than in type NB esophagitis. However, there were no significant intergroup differences in the incidences of other predisposing factors, such as diabetic ketoacidosis or esophageal hernias. These findings suggest that AEMLs are caused by acid reflux and peripheral vascular insufficiency, the latter being more associated with type B esophagitis by its etiology. In addition, blood lactate may indicate the severity of AEML, leading to black esophagitis.
| Original language | English |
|---|---|
| Pages (from-to) | 642-646 |
| Number of pages | 5 |
| Journal | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology |
| Volume | 113 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Apr 1 2016 |
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All Science Journal Classification (ASJC) codes
- Gastroenterology
Cite this
Clinical features and pathophysiology of acute esophageal mucosal lesion. / Ihara, Yutaro; Hizawa, Kazuoki; Fujita, Kouhei; Matsuno, Yuichi; Sakuma, Tsutomu; Esaki, Motohiro; Iida, Mitsuo.
In: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology, Vol. 113, No. 4, 01.04.2016, p. 642-646.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Clinical features and pathophysiology of acute esophageal mucosal lesion
AU - Ihara, Yutaro
AU - Hizawa, Kazuoki
AU - Fujita, Kouhei
AU - Matsuno, Yuichi
AU - Sakuma, Tsutomu
AU - Esaki, Motohiro
AU - Iida, Mitsuo
PY - 2016/4/1
Y1 - 2016/4/1
N2 - Acute esophageal mucosal lesions (AEMLs) are categorized into black esophagitis (type B) and non-black esophagitis (type NB) on endoscopy. To clarify the distinct pathophysiology, we compared the clinical features and hematological findings at onset among 17 patients with type B esophagitis and 6 patients with type NB esophagitis. In type B esophagitis, time to endoscopy after onset was significantly shorter, and blood levels of lactate, urea nitrogen, creatinine, and glucose were higher than in type NB esophagitis. However, there were no significant intergroup differences in the incidences of other predisposing factors, such as diabetic ketoacidosis or esophageal hernias. These findings suggest that AEMLs are caused by acid reflux and peripheral vascular insufficiency, the latter being more associated with type B esophagitis by its etiology. In addition, blood lactate may indicate the severity of AEML, leading to black esophagitis.
AB - Acute esophageal mucosal lesions (AEMLs) are categorized into black esophagitis (type B) and non-black esophagitis (type NB) on endoscopy. To clarify the distinct pathophysiology, we compared the clinical features and hematological findings at onset among 17 patients with type B esophagitis and 6 patients with type NB esophagitis. In type B esophagitis, time to endoscopy after onset was significantly shorter, and blood levels of lactate, urea nitrogen, creatinine, and glucose were higher than in type NB esophagitis. However, there were no significant intergroup differences in the incidences of other predisposing factors, such as diabetic ketoacidosis or esophageal hernias. These findings suggest that AEMLs are caused by acid reflux and peripheral vascular insufficiency, the latter being more associated with type B esophagitis by its etiology. In addition, blood lactate may indicate the severity of AEML, leading to black esophagitis.
UR - http://www.scopus.com/inward/record.url?scp=84983732468&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84983732468&partnerID=8YFLogxK
U2 - 10.11405/nisshoshi.113.642
DO - 10.11405/nisshoshi.113.642
M3 - Article
C2 - 27052393
AN - SCOPUS:84983732468
VL - 113
SP - 642
EP - 646
JO - Japanese Journal of Gastroenterology
JF - Japanese Journal of Gastroenterology
SN - 0446-6586
IS - 4
ER -