Clinical outcome of the laparoscopic surgery for stage II and III colorectal cancer

Takeshi Naitoh, Takashi Tsuchiya, Hiroshi Honda, Masaya Oikawa, Yuko Saito, Yasuhiro Hasegawa

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Background: Laparoscopic colorectal cancer surgery has become widely accepted recently. However, the oncological validity of this surgery has not yet been well analyzed, especially for advanced cancer. The aim of this study is to assess the clinical outcome of laparoscopic surgery for stage II/III colorectal cancer in our hospital. Patients and methods: Between June 1999 and August 2006, 321 patients underwent laparoscopic colorectal cancer surgery in our hospital; of those 121 cases whose pathological findings revealed stage II/III were included in this study. Among these cases, we assessed a short-term outcome and a medium-term outcome in terms of survival evaluation. Results: The male:female ratio was 73:48, and mean age of patients was 62.4 years. Thirteen tumors were located in the cecum, 29 in the ascending colon, five in the transverse colon, one in the descending colon, 43 in the sigmoid colon, and 30 in the rectum. Average duration of operation was 184 minutes, and mean estimated blood loss was 53.5 ml. Five patients (4.1%) were converted to open procedures. No intraoperative complication was observed but eight complications (6.6%) occurred postoperatively. Forty-two cases were classified as stage II, 62 as stage IIIA /B, and 17 as stage IIIC. Five patients died of cancer relapse (4.1%), and 18 cases had recurrence of disease (14.9%), to date. No port-site recurrence was detected. Overall five-year survival was 95.7% in stage II, 84.1% in stage IIIA/B, 70.0% in stage IIIC. Meanwhile disease-free five-year survival was 75.6% in stage II, 80.1% in stage IIIA/B, and 66.8% in stage IIIC. No significant difference was observed between stages, in terms of either overall or disease-free survival. Conclusion: Although further evaluation is required, laparoscopic surgery for stage II/III colorectal cancer is safe and would be an oncologically adequate procedure.

Original languageEnglish
Pages (from-to)950-954
Number of pages5
JournalSurgical Endoscopy and Other Interventional Techniques
Volume22
Issue number4
DOIs
Publication statusPublished - Apr 1 2008
Externally publishedYes

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Laparoscopy
Colorectal Neoplasms
Colorectal Surgery
Recurrence
Survival
Descending Colon
Ascending Colon
Neoplasms
Transverse Colon
Cecum
Intraoperative Complications
Sigmoid Colon
Rectum
Disease-Free Survival

All Science Journal Classification (ASJC) codes

  • Surgery

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Clinical outcome of the laparoscopic surgery for stage II and III colorectal cancer. / Naitoh, Takeshi; Tsuchiya, Takashi; Honda, Hiroshi; Oikawa, Masaya; Saito, Yuko; Hasegawa, Yasuhiro.

In: Surgical Endoscopy and Other Interventional Techniques, Vol. 22, No. 4, 01.04.2008, p. 950-954.

Research output: Contribution to journalArticle

Naitoh, Takeshi ; Tsuchiya, Takashi ; Honda, Hiroshi ; Oikawa, Masaya ; Saito, Yuko ; Hasegawa, Yasuhiro. / Clinical outcome of the laparoscopic surgery for stage II and III colorectal cancer. In: Surgical Endoscopy and Other Interventional Techniques. 2008 ; Vol. 22, No. 4. pp. 950-954.
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abstract = "Background: Laparoscopic colorectal cancer surgery has become widely accepted recently. However, the oncological validity of this surgery has not yet been well analyzed, especially for advanced cancer. The aim of this study is to assess the clinical outcome of laparoscopic surgery for stage II/III colorectal cancer in our hospital. Patients and methods: Between June 1999 and August 2006, 321 patients underwent laparoscopic colorectal cancer surgery in our hospital; of those 121 cases whose pathological findings revealed stage II/III were included in this study. Among these cases, we assessed a short-term outcome and a medium-term outcome in terms of survival evaluation. Results: The male:female ratio was 73:48, and mean age of patients was 62.4 years. Thirteen tumors were located in the cecum, 29 in the ascending colon, five in the transverse colon, one in the descending colon, 43 in the sigmoid colon, and 30 in the rectum. Average duration of operation was 184 minutes, and mean estimated blood loss was 53.5 ml. Five patients (4.1{\%}) were converted to open procedures. No intraoperative complication was observed but eight complications (6.6{\%}) occurred postoperatively. Forty-two cases were classified as stage II, 62 as stage IIIA /B, and 17 as stage IIIC. Five patients died of cancer relapse (4.1{\%}), and 18 cases had recurrence of disease (14.9{\%}), to date. No port-site recurrence was detected. Overall five-year survival was 95.7{\%} in stage II, 84.1{\%} in stage IIIA/B, 70.0{\%} in stage IIIC. Meanwhile disease-free five-year survival was 75.6{\%} in stage II, 80.1{\%} in stage IIIA/B, and 66.8{\%} in stage IIIC. No significant difference was observed between stages, in terms of either overall or disease-free survival. Conclusion: Although further evaluation is required, laparoscopic surgery for stage II/III colorectal cancer is safe and would be an oncologically adequate procedure.",
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T1 - Clinical outcome of the laparoscopic surgery for stage II and III colorectal cancer

AU - Naitoh, Takeshi

AU - Tsuchiya, Takashi

AU - Honda, Hiroshi

AU - Oikawa, Masaya

AU - Saito, Yuko

AU - Hasegawa, Yasuhiro

PY - 2008/4/1

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N2 - Background: Laparoscopic colorectal cancer surgery has become widely accepted recently. However, the oncological validity of this surgery has not yet been well analyzed, especially for advanced cancer. The aim of this study is to assess the clinical outcome of laparoscopic surgery for stage II/III colorectal cancer in our hospital. Patients and methods: Between June 1999 and August 2006, 321 patients underwent laparoscopic colorectal cancer surgery in our hospital; of those 121 cases whose pathological findings revealed stage II/III were included in this study. Among these cases, we assessed a short-term outcome and a medium-term outcome in terms of survival evaluation. Results: The male:female ratio was 73:48, and mean age of patients was 62.4 years. Thirteen tumors were located in the cecum, 29 in the ascending colon, five in the transverse colon, one in the descending colon, 43 in the sigmoid colon, and 30 in the rectum. Average duration of operation was 184 minutes, and mean estimated blood loss was 53.5 ml. Five patients (4.1%) were converted to open procedures. No intraoperative complication was observed but eight complications (6.6%) occurred postoperatively. Forty-two cases were classified as stage II, 62 as stage IIIA /B, and 17 as stage IIIC. Five patients died of cancer relapse (4.1%), and 18 cases had recurrence of disease (14.9%), to date. No port-site recurrence was detected. Overall five-year survival was 95.7% in stage II, 84.1% in stage IIIA/B, 70.0% in stage IIIC. Meanwhile disease-free five-year survival was 75.6% in stage II, 80.1% in stage IIIA/B, and 66.8% in stage IIIC. No significant difference was observed between stages, in terms of either overall or disease-free survival. Conclusion: Although further evaluation is required, laparoscopic surgery for stage II/III colorectal cancer is safe and would be an oncologically adequate procedure.

AB - Background: Laparoscopic colorectal cancer surgery has become widely accepted recently. However, the oncological validity of this surgery has not yet been well analyzed, especially for advanced cancer. The aim of this study is to assess the clinical outcome of laparoscopic surgery for stage II/III colorectal cancer in our hospital. Patients and methods: Between June 1999 and August 2006, 321 patients underwent laparoscopic colorectal cancer surgery in our hospital; of those 121 cases whose pathological findings revealed stage II/III were included in this study. Among these cases, we assessed a short-term outcome and a medium-term outcome in terms of survival evaluation. Results: The male:female ratio was 73:48, and mean age of patients was 62.4 years. Thirteen tumors were located in the cecum, 29 in the ascending colon, five in the transverse colon, one in the descending colon, 43 in the sigmoid colon, and 30 in the rectum. Average duration of operation was 184 minutes, and mean estimated blood loss was 53.5 ml. Five patients (4.1%) were converted to open procedures. No intraoperative complication was observed but eight complications (6.6%) occurred postoperatively. Forty-two cases were classified as stage II, 62 as stage IIIA /B, and 17 as stage IIIC. Five patients died of cancer relapse (4.1%), and 18 cases had recurrence of disease (14.9%), to date. No port-site recurrence was detected. Overall five-year survival was 95.7% in stage II, 84.1% in stage IIIA/B, 70.0% in stage IIIC. Meanwhile disease-free five-year survival was 75.6% in stage II, 80.1% in stage IIIA/B, and 66.8% in stage IIIC. No significant difference was observed between stages, in terms of either overall or disease-free survival. Conclusion: Although further evaluation is required, laparoscopic surgery for stage II/III colorectal cancer is safe and would be an oncologically adequate procedure.

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