Clinical Outcomes and Prognostic Factors After Surgery for Non-Occlusive Mesenteric Ischemia: a Multicenter Study

Takafumi Yukaya, Hiroshi Saeki, Kenji Taketani, Koji Ando, Satoshi Ida, Yasue Kimura, Eiji Oki, Mitsuhiro Yasuda, Masaru Morita, Ken Shirabe, Yoshihiko Maehara

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)


Background: To date, no large-scale study has been undertaken to understand the clinical features of non-occlusive mesenteric ischemia (NOMI) after surgery. We thus performed a multicenter investigation to clarify the clinical outcomes and prognostic factors of NOMI. Patients and Methods: Clinical databases from 22 Japanese facilities were reviewed for evaluation of patients who received surgery for NOMI between 2004 and 2012. NOMI patients (n = 51) were divided into two groups: group I (n = 28) consisted of patients who survived, and group II (n = 23) consisted of patients who did not survived. Prognostic factors were compared between the two groups. Results: NOMI surgery represented 0.04 % of the total number of operations performed in this time period. The overall mortality rate for NOMI surgery was 45 %. Hemodialysis was a significant negative prognostic factor (p = 0.027). Preoperative elevation of transaminases, potassium, and white blood cell count, as well as metabolic acidosis and colon ischemia was poor prognostic factors. The mean Physiological and Operative Severity Score for the enumeration of Mortality and Morbidity (POSSUM) score of group I versus group II was 54.5 ± 3.6 and 85.2 ± 4.1, respectively (p < 0.001). Conclusions: Currently, NOMI surgery has a 45 % mortality rate. POSSUM scores can be used to predict the clinical outcome of patients who receive NOMI surgery.

Original languageEnglish
Pages (from-to)1642-1647
Number of pages6
JournalJournal of Gastrointestinal Surgery
Issue number9
Publication statusPublished - Sept 1 2014

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology


Dive into the research topics of 'Clinical Outcomes and Prognostic Factors After Surgery for Non-Occlusive Mesenteric Ischemia: a Multicenter Study'. Together they form a unique fingerprint.

Cite this