Clinical outcomes from hepatic artery stenting in liver transplantation

Takehisa Ueno, Greg Jones, Adrian Martin, Toru Ikegami, Edmund Q. Sanchez, Srinath Chinnakotla, Henry B. Randall, Marlon F. Levy, Robert M. Goldstein, Goran B. Klintmalm

Research output: Contribution to journalArticle

60 Citations (Scopus)

Abstract

Hepatic artery stenosis after liver transplantation may affect liver function and result in hepatic artery thrombosis. Surgical reconstruction has been the first choice for treatment. Interventional radiologic technique can be used, but there is no report on long-term outcome. The aim of this paper is to assess current outcome and complications of hepatic artery stenting. Twenty-six adult patients were stented for hepatic artery stenosis between 1998 and 2003. Nine patients had previous surgical reconstruction for hepatic artery stenosis. Seventeen patients suffered newly developed hepatic artery stenosis. Three patients were retransplanted. After stenting, the patients were followed by Doppler ultrasound at day 1, 1 month, and 6 months. Angiography was scheduled in 6 months. Four patients died within 2 months. The other 22 patients were followed for mean 31 ± 14 months (8-71 months). One of 22 patients died from renal failure 2 years later. Twelve patients' hepatic arteries looked normal after stenting. Restenosis was seen in 8 patients (36%). Other complications were artery thrombosis (n = 1) and long segment stricture (n = 1). In 2 patients (25%) restenosis resulted in thrombosis. Six of the 8 patients who developed recurrent stenosis were successfully treated interventionally: restent (n = 5) and balloon dilation (n = 3). However, 3 patients (38%) restenosed. Kaplan-Meier complication-free survival was 54% at 1 year after stenting. In conclusion, hepatic artery stenting is a viable treatment for hepatic artery stenosis with reasonable results. Stenting is useful as adjuvant treatment after surgical revision.

Original languageEnglish
Pages (from-to)422-427
Number of pages6
JournalLiver Transplantation
Volume12
Issue number3
DOIs
Publication statusPublished - Mar 1 2006

Fingerprint

Hepatic Artery
Liver Transplantation
Pathologic Constriction
Thrombosis
Doppler Ultrasonography
Reoperation
Renal Insufficiency
Dilatation
Angiography
Therapeutics
Arteries

All Science Journal Classification (ASJC) codes

  • Surgery
  • Hepatology
  • Transplantation

Cite this

Ueno, T., Jones, G., Martin, A., Ikegami, T., Sanchez, E. Q., Chinnakotla, S., ... Klintmalm, G. B. (2006). Clinical outcomes from hepatic artery stenting in liver transplantation. Liver Transplantation, 12(3), 422-427. https://doi.org/10.1002/lt.20628

Clinical outcomes from hepatic artery stenting in liver transplantation. / Ueno, Takehisa; Jones, Greg; Martin, Adrian; Ikegami, Toru; Sanchez, Edmund Q.; Chinnakotla, Srinath; Randall, Henry B.; Levy, Marlon F.; Goldstein, Robert M.; Klintmalm, Goran B.

In: Liver Transplantation, Vol. 12, No. 3, 01.03.2006, p. 422-427.

Research output: Contribution to journalArticle

Ueno, T, Jones, G, Martin, A, Ikegami, T, Sanchez, EQ, Chinnakotla, S, Randall, HB, Levy, MF, Goldstein, RM & Klintmalm, GB 2006, 'Clinical outcomes from hepatic artery stenting in liver transplantation', Liver Transplantation, vol. 12, no. 3, pp. 422-427. https://doi.org/10.1002/lt.20628
Ueno T, Jones G, Martin A, Ikegami T, Sanchez EQ, Chinnakotla S et al. Clinical outcomes from hepatic artery stenting in liver transplantation. Liver Transplantation. 2006 Mar 1;12(3):422-427. https://doi.org/10.1002/lt.20628
Ueno, Takehisa ; Jones, Greg ; Martin, Adrian ; Ikegami, Toru ; Sanchez, Edmund Q. ; Chinnakotla, Srinath ; Randall, Henry B. ; Levy, Marlon F. ; Goldstein, Robert M. ; Klintmalm, Goran B. / Clinical outcomes from hepatic artery stenting in liver transplantation. In: Liver Transplantation. 2006 ; Vol. 12, No. 3. pp. 422-427.
@article{a4c0be35fc4b4fa8a19874d2104c4f30,
title = "Clinical outcomes from hepatic artery stenting in liver transplantation",
abstract = "Hepatic artery stenosis after liver transplantation may affect liver function and result in hepatic artery thrombosis. Surgical reconstruction has been the first choice for treatment. Interventional radiologic technique can be used, but there is no report on long-term outcome. The aim of this paper is to assess current outcome and complications of hepatic artery stenting. Twenty-six adult patients were stented for hepatic artery stenosis between 1998 and 2003. Nine patients had previous surgical reconstruction for hepatic artery stenosis. Seventeen patients suffered newly developed hepatic artery stenosis. Three patients were retransplanted. After stenting, the patients were followed by Doppler ultrasound at day 1, 1 month, and 6 months. Angiography was scheduled in 6 months. Four patients died within 2 months. The other 22 patients were followed for mean 31 ± 14 months (8-71 months). One of 22 patients died from renal failure 2 years later. Twelve patients' hepatic arteries looked normal after stenting. Restenosis was seen in 8 patients (36{\%}). Other complications were artery thrombosis (n = 1) and long segment stricture (n = 1). In 2 patients (25{\%}) restenosis resulted in thrombosis. Six of the 8 patients who developed recurrent stenosis were successfully treated interventionally: restent (n = 5) and balloon dilation (n = 3). However, 3 patients (38{\%}) restenosed. Kaplan-Meier complication-free survival was 54{\%} at 1 year after stenting. In conclusion, hepatic artery stenting is a viable treatment for hepatic artery stenosis with reasonable results. Stenting is useful as adjuvant treatment after surgical revision.",
author = "Takehisa Ueno and Greg Jones and Adrian Martin and Toru Ikegami and Sanchez, {Edmund Q.} and Srinath Chinnakotla and Randall, {Henry B.} and Levy, {Marlon F.} and Goldstein, {Robert M.} and Klintmalm, {Goran B.}",
year = "2006",
month = "3",
day = "1",
doi = "10.1002/lt.20628",
language = "English",
volume = "12",
pages = "422--427",
journal = "Liver Transplantation",
issn = "1527-6465",
publisher = "John Wiley and Sons Ltd",
number = "3",

}

TY - JOUR

T1 - Clinical outcomes from hepatic artery stenting in liver transplantation

AU - Ueno, Takehisa

AU - Jones, Greg

AU - Martin, Adrian

AU - Ikegami, Toru

AU - Sanchez, Edmund Q.

AU - Chinnakotla, Srinath

AU - Randall, Henry B.

AU - Levy, Marlon F.

AU - Goldstein, Robert M.

AU - Klintmalm, Goran B.

PY - 2006/3/1

Y1 - 2006/3/1

N2 - Hepatic artery stenosis after liver transplantation may affect liver function and result in hepatic artery thrombosis. Surgical reconstruction has been the first choice for treatment. Interventional radiologic technique can be used, but there is no report on long-term outcome. The aim of this paper is to assess current outcome and complications of hepatic artery stenting. Twenty-six adult patients were stented for hepatic artery stenosis between 1998 and 2003. Nine patients had previous surgical reconstruction for hepatic artery stenosis. Seventeen patients suffered newly developed hepatic artery stenosis. Three patients were retransplanted. After stenting, the patients were followed by Doppler ultrasound at day 1, 1 month, and 6 months. Angiography was scheduled in 6 months. Four patients died within 2 months. The other 22 patients were followed for mean 31 ± 14 months (8-71 months). One of 22 patients died from renal failure 2 years later. Twelve patients' hepatic arteries looked normal after stenting. Restenosis was seen in 8 patients (36%). Other complications were artery thrombosis (n = 1) and long segment stricture (n = 1). In 2 patients (25%) restenosis resulted in thrombosis. Six of the 8 patients who developed recurrent stenosis were successfully treated interventionally: restent (n = 5) and balloon dilation (n = 3). However, 3 patients (38%) restenosed. Kaplan-Meier complication-free survival was 54% at 1 year after stenting. In conclusion, hepatic artery stenting is a viable treatment for hepatic artery stenosis with reasonable results. Stenting is useful as adjuvant treatment after surgical revision.

AB - Hepatic artery stenosis after liver transplantation may affect liver function and result in hepatic artery thrombosis. Surgical reconstruction has been the first choice for treatment. Interventional radiologic technique can be used, but there is no report on long-term outcome. The aim of this paper is to assess current outcome and complications of hepatic artery stenting. Twenty-six adult patients were stented for hepatic artery stenosis between 1998 and 2003. Nine patients had previous surgical reconstruction for hepatic artery stenosis. Seventeen patients suffered newly developed hepatic artery stenosis. Three patients were retransplanted. After stenting, the patients were followed by Doppler ultrasound at day 1, 1 month, and 6 months. Angiography was scheduled in 6 months. Four patients died within 2 months. The other 22 patients were followed for mean 31 ± 14 months (8-71 months). One of 22 patients died from renal failure 2 years later. Twelve patients' hepatic arteries looked normal after stenting. Restenosis was seen in 8 patients (36%). Other complications were artery thrombosis (n = 1) and long segment stricture (n = 1). In 2 patients (25%) restenosis resulted in thrombosis. Six of the 8 patients who developed recurrent stenosis were successfully treated interventionally: restent (n = 5) and balloon dilation (n = 3). However, 3 patients (38%) restenosed. Kaplan-Meier complication-free survival was 54% at 1 year after stenting. In conclusion, hepatic artery stenting is a viable treatment for hepatic artery stenosis with reasonable results. Stenting is useful as adjuvant treatment after surgical revision.

UR - http://www.scopus.com/inward/record.url?scp=33645325638&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33645325638&partnerID=8YFLogxK

U2 - 10.1002/lt.20628

DO - 10.1002/lt.20628

M3 - Article

VL - 12

SP - 422

EP - 427

JO - Liver Transplantation

JF - Liver Transplantation

SN - 1527-6465

IS - 3

ER -