Clinical relevance of phase of steady-state VEPs to P100 latency of transient VEPs

Shozo Tobimatsu, Shizuka Tashima-Kurita, Miyuki Nakayama-Hiromatsu, Motohiro Kato

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Pattern visual evoked potentials (VEPs) to transient and steady-state stimulation were recorded in 10 normal subjects at 4 levels of luminance (180, 57, 22 and 11 cd/m2). VEPs were also recorded in 5 patients with optic neuropathy at a fixed luminance (180 cd/m2). The relationship between P100 latency of transient VEPs (T-VEPs) and the phase of steady-state VEPs (S-VEPs) was analyzed. As luminance decreased in normal subjects, P100 latency was prolonged and the phase lag increased. A significant linear relationship between the P100 latency and phase was found. Patients showed both the prolonged P100 latency and the delayed phase. The simple linear regression line of the phase-P100 latency function of normal subjects closely matched the patients' values. These results suggest that changes in the phase may be equivalent to changes in the P100 latency. S-VEPs, therefore, may be clinically useful in assessing visual function.

Original languageEnglish
Pages (from-to)89-93
Number of pages5
JournalElectroencephalography and Clinical Neurophysiology/ Evoked Potentials
Volume80
Issue number2
DOIs
Publication statusPublished - Jan 1 1991
Externally publishedYes

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All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Clinical Neurology

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