Abstract
Chronic nonspecific multiple ulcers of the small intestine is a rare but distinct clinical condition, characterized by multiple small intestinal ulcers of nonspecific histology and chronic, persistent gastrointestinal bleeding without nonsteroidal anti-inflammatory drug use. However, because of the term “nonspecific” in its nomenclature, some gastroenterologists have misinterpreted the disease as the condition with small intestinal ulcers caused by undetermined etiologies without considering clinical features. Such misinterpretation has led to the heterogeneity of clinicopathologic features of the disease, as well as to ambiguity regarding a possible genetic contribution. It thus seems necessary to recognize the clinical entity of the disease precisely to avoid misinterpretation. In this review, we describe the clinicopathologic features, differential diagnosis, and the possibility of a genetic contribution to the disease.
| Original language | English |
|---|---|
| Pages (from-to) | 57-62 |
| Number of pages | 6 |
| Journal | Clinical Journal of Gastroenterology |
| Volume | 8 |
| Issue number | 2 |
| DOIs | |
| Publication status | Published - Apr 1 2015 |
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All Science Journal Classification (ASJC) codes
- Gastroenterology
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Clinicopathologic features of chronic nonspecific multiple ulcers of the small intestine. / Esaki, Motohiro; Umeno, Junji; Kitazono, Takanari; Matsumoto, Takayuki.
In: Clinical Journal of Gastroenterology, Vol. 8, No. 2, 01.04.2015, p. 57-62.Research output: Contribution to journal › Review article
}
TY - JOUR
T1 - Clinicopathologic features of chronic nonspecific multiple ulcers of the small intestine
AU - Esaki, Motohiro
AU - Umeno, Junji
AU - Kitazono, Takanari
AU - Matsumoto, Takayuki
PY - 2015/4/1
Y1 - 2015/4/1
N2 - Chronic nonspecific multiple ulcers of the small intestine is a rare but distinct clinical condition, characterized by multiple small intestinal ulcers of nonspecific histology and chronic, persistent gastrointestinal bleeding without nonsteroidal anti-inflammatory drug use. However, because of the term “nonspecific” in its nomenclature, some gastroenterologists have misinterpreted the disease as the condition with small intestinal ulcers caused by undetermined etiologies without considering clinical features. Such misinterpretation has led to the heterogeneity of clinicopathologic features of the disease, as well as to ambiguity regarding a possible genetic contribution. It thus seems necessary to recognize the clinical entity of the disease precisely to avoid misinterpretation. In this review, we describe the clinicopathologic features, differential diagnosis, and the possibility of a genetic contribution to the disease.
AB - Chronic nonspecific multiple ulcers of the small intestine is a rare but distinct clinical condition, characterized by multiple small intestinal ulcers of nonspecific histology and chronic, persistent gastrointestinal bleeding without nonsteroidal anti-inflammatory drug use. However, because of the term “nonspecific” in its nomenclature, some gastroenterologists have misinterpreted the disease as the condition with small intestinal ulcers caused by undetermined etiologies without considering clinical features. Such misinterpretation has led to the heterogeneity of clinicopathologic features of the disease, as well as to ambiguity regarding a possible genetic contribution. It thus seems necessary to recognize the clinical entity of the disease precisely to avoid misinterpretation. In this review, we describe the clinicopathologic features, differential diagnosis, and the possibility of a genetic contribution to the disease.
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UR - http://www.scopus.com/inward/citedby.url?scp=84939956992&partnerID=8YFLogxK
U2 - 10.1007/s12328-015-0559-x
DO - 10.1007/s12328-015-0559-x
M3 - Review article
C2 - 25788296
AN - SCOPUS:84939956992
VL - 8
SP - 57
EP - 62
JO - Clinical Journal of Gastroenterology
JF - Clinical Journal of Gastroenterology
SN - 1865-7257
IS - 2
ER -