Clinicopathological Characteristics of Esophageal Squamous Cell Carcinoma in Patients Younger Than 50 years

Yuta Kasagi, Masaru Morita, Hajime Otsu, Hiroyuki Kawano, Koji Ando, Yukiharu Hiyoshi, Shuhei Ito, Yuji Miyamoto, Hiroshi Saeki, Eiji Oki, Yoshihiko Maehara

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Abstract

Purpose: This study clarifies age differences in clinicopathologic characteristics and risk factor exposure of patients who have undergone esophagectomy for esophageal cancer (EC).

Methods: Clinical results of esophagectomy were compared between 22 patients younger than 50years of age (Group I) and 327 patients older than 50 years of age (Group II) with esophageal squamous cell carcinoma.

Results: The two groups did not significantly differ in clinicopathological characteristics, including prognosis. Postoperative pulmonary complication incidence rates were 4.2% (Group I) and 14.4% (Group II). In Group I, the incidence of multiple ECs was 36.4%, and association with head and neck cancer was 31.8%, which were significantly higher than in Group II (13.4%, p=0.021; and 9.2%, p=0.015, respectively). Furthermore, the patients in Group I with multiple cancers were almost all heavy smokers and/or users of alcohol.

Conclusions: These results suggest that multiple upper aerodigestive tract cancers are associated with heavy exposure to risk factors in patients younger than 50years of age.

Original languageEnglish
Pages (from-to)311-315
Number of pages5
JournalAnnals of Surgical Oncology
Volume22
Issue number1
DOIs
Publication statusPublished - Jan 1 2015

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Esophagectomy
Age Groups
Incidence
Esophageal Neoplasms
Head and Neck Neoplasms
Neoplasms
Alcohols
Esophageal Squamous Cell Carcinoma
Lung

All Science Journal Classification (ASJC) codes

  • Surgery
  • Oncology

Cite this

Clinicopathological Characteristics of Esophageal Squamous Cell Carcinoma in Patients Younger Than 50 years. / Kasagi, Yuta; Morita, Masaru; Otsu, Hajime; Kawano, Hiroyuki; Ando, Koji; Hiyoshi, Yukiharu; Ito, Shuhei; Miyamoto, Yuji; Saeki, Hiroshi; Oki, Eiji; Maehara, Yoshihiko.

In: Annals of Surgical Oncology, Vol. 22, No. 1, 01.01.2015, p. 311-315.

Research output: Contribution to journalArticle

Kasagi, Yuta ; Morita, Masaru ; Otsu, Hajime ; Kawano, Hiroyuki ; Ando, Koji ; Hiyoshi, Yukiharu ; Ito, Shuhei ; Miyamoto, Yuji ; Saeki, Hiroshi ; Oki, Eiji ; Maehara, Yoshihiko. / Clinicopathological Characteristics of Esophageal Squamous Cell Carcinoma in Patients Younger Than 50 years. In: Annals of Surgical Oncology. 2015 ; Vol. 22, No. 1. pp. 311-315.
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AU - Hiyoshi, Yukiharu

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AU - Oki, Eiji

AU - Maehara, Yoshihiko

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