TY - JOUR
T1 - Cloning and characterization of bovine cytochrome P-450(11β) genes
AU - Hashimoto, Toshihide
AU - Morohashi, Ken ichirou
AU - Omura, Tsuneo
PY - 1989/5
Y1 - 1989/5
N2 - We isolated 4 different clones of the P-450(11β) gene from a bovine genomic library. These genomic clones were highly homologous with each other. Two of the isolated clones were pseudogenes. Determination of its nucleotide sequences indicated that the bovine P-450(11β) gene is divided into 9 exons by 8 introns and that it is about 8.5 kb in total length. The number of exons and the locations of intron insertion into the P-450(11β) gene are identical with those in the case of P-450(SCC), but different from those of other microsomal P-450s.
AB - We isolated 4 different clones of the P-450(11β) gene from a bovine genomic library. These genomic clones were highly homologous with each other. Two of the isolated clones were pseudogenes. Determination of its nucleotide sequences indicated that the bovine P-450(11β) gene is divided into 9 exons by 8 introns and that it is about 8.5 kb in total length. The number of exons and the locations of intron insertion into the P-450(11β) gene are identical with those in the case of P-450(SCC), but different from those of other microsomal P-450s.
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U2 - 10.1093/oxfordjournals.jbchem.a122725
DO - 10.1093/oxfordjournals.jbchem.a122725
M3 - Article
C2 - 2753866
AN - SCOPUS:0024381417
SN - 0021-924X
VL - 105
SP - 676
EP - 679
JO - Journal of Biochemistry
JF - Journal of Biochemistry
IS - 5
ER -