Cloning and characterization of bovine cytochrome P-450(11β) genes

Toshihide Hashimoto, Ken-Ichirou Morohashi, Tsuneo Omura

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Abstract

We isolated 4 different clones of the P-450(11β) gene from a bovine genomic library. These genomic clones were highly homologous with each other. Two of the isolated clones were pseudogenes. Determination of its nucleotide sequences indicated that the bovine P-450(11β) gene is divided into 9 exons by 8 introns and that it is about 8.5 kb in total length. The number of exons and the locations of intron insertion into the P-450(11β) gene are identical with those in the case of P-450(SCC), but different from those of other microsomal P-450s.

Original languageEnglish
Pages (from-to)676-679
Number of pages4
JournalJournal of Biochemistry
Volume105
Issue number5
DOIs
Publication statusPublished - Jan 1 1989

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Molecular Biology

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