Cloning and sequencing of the cDNA encoding human glutaredoxin

M. Rohan Fernando, Hideki Sumimoto, Hiroki Nanri, Shun ichiro Kawabata, Sadaaki Iwanaga, Shigeki Minakami, Yasuyuki Fukumaki, Koichiro Takeshige

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Abstract

Glutaredoxin (thioltransferase) is a small, heat-stable protein, which is involved in thiol/disulfide exchange reactions. We have isolated a cDNA that encodes glutaredoxin from a human brain cDNA library. The encoded protein contains 106 amino acids with a calculated molecular mass of 11.76 kDa and an isoelectric point of 8.09. The amino acid sequence deduced from the cDNA is more than 80% identical to those of other mammalian glutaredoxins.

Original languageEnglish
Pages (from-to)229-231
Number of pages3
JournalBBA - Gene Structure and Expression
Volume1218
Issue number2
DOIs
Publication statusPublished - Jun 21 1994

All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Biophysics
  • Biochemistry
  • Genetics

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    Fernando, M. R., Sumimoto, H., Nanri, H., Kawabata, S. I., Iwanaga, S., Minakami, S., Fukumaki, Y., & Takeshige, K. (1994). Cloning and sequencing of the cDNA encoding human glutaredoxin. BBA - Gene Structure and Expression, 1218(2), 229-231. https://doi.org/10.1016/0167-4781(94)90019-1