Co(II)-salen-catalyzed highly cis- and enantioselective cyclopropanation

Tatsuo Niimi, Tatsuya Uchida, Ryo Irie, Tsutomu Katsuki

Research output: Contribution to journalArticlepeer-review

110 Citations (Scopus)

Abstract

The reactions of styrene derivatives and t-butyl α-diazoacetate using (R,R)-(salen)cobalt(II) complex 6 as a catalyst in the presence of N- methylimidazole gave the corresponding cyclopropanecarboxylates with excellent enantio- (>95% ee) and high cis-stereoselectivity (98%) as well as good chemical yields. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)3647-3651
Number of pages5
JournalTetrahedron Letters
Volume41
Issue number19
DOIs
Publication statusPublished - May 6 2000

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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