Colony-stimulating factor - in vitro and in vivo effect

Y. Niho; S. Okamura; M. Harada; T. Shibuya; N. Kimura; T. Tanaka; K. Akashi

Colony-stimulating factor - in vitro and in vivo effect

Y. Niho, S. Okamura, M. Harada, T. Shibuya, N. Kimura, T. Tanaka, K. Akashi

Kyushu University Hospital

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Colony stimulating factor (CSF) was initially named for the activity or factor which modulated colony formations of mature granulocytes originated from a progenitor cell in bone marrow in a culture dish. In this article, we described a detective system for CSF, CSF-producing tumor which strongly suggested to us that CSF was not only a factor in vitro phenomenon but also a factor working actually in vivo. Finally, we presented a few experiences of administration of recombinant CSF to experimental animals and finally several cases of clinical trials of CSF which seem to be very potent and able agents for granulopenic patients.

Original language	English
Title of host publication	New horizons of tumor immunotherapy
Subtitle of host publication	proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852
Editors	M. Torisu, T. Yoshida, M. Torisu, T. Yoshida
Publisher	Elsevier Science Publishers B.V.
Pages	501-521
Number of pages	21
ISBN (Print)	0444813489
Publication status	Published - 1989
Event	The International Symposium on new horizons of tumor immunotherapy - Duration: Nov 30 1988 → Dec 2 1988

Publication series

Name	New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852

Other

Other	The International Symposium on new horizons of tumor immunotherapy
Period	11/30/88 → 12/2/88

All Science Journal Classification (ASJC) codes

Medicine(all)

Cite this

Niho, Y., Okamura, S., Harada, M., Shibuya, T., Kimura, N., Tanaka, T., & Akashi, K. (1989). Colony-stimulating factor - in vitro and in vivo effect. In M. Torisu, T. Yoshida, M. Torisu, & T. Yoshida (Eds.), New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852 (pp. 501-521). (New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852). Elsevier Science Publishers B.V..

Colony-stimulating factor - in vitro and in vivo effect. / Niho, Y.; Okamura, S.; Harada, M. et al.
New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852. ed. / M. Torisu; T. Yoshida; M. Torisu; T. Yoshida. Elsevier Science Publishers B.V., 1989. p. 501-521 (New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Niho, Y, Okamura, S, Harada, M, Shibuya, T, Kimura, N, Tanaka, T & Akashi, K 1989, Colony-stimulating factor - in vitro and in vivo effect. in M Torisu, T Yoshida, M Torisu & T Yoshida (eds), New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852. New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852, Elsevier Science Publishers B.V., pp. 501-521, The International Symposium on new horizons of tumor immunotherapy, 11/30/88.

Niho Y, Okamura S, Harada M, Shibuya T, Kimura N, Tanaka T et al. Colony-stimulating factor - in vitro and in vivo effect. In Torisu M, Yoshida T, Torisu M, Yoshida T, editors, New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852. Elsevier Science Publishers B.V. 1989. p. 501-521. (New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852).

Niho, Y. ; Okamura, S. ; Harada, M. et al. / Colony-stimulating factor - in vitro and in vivo effect. New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852. editor / M. Torisu ; T. Yoshida ; M. Torisu ; T. Yoshida. Elsevier Science Publishers B.V., 1989. pp. 501-521 (New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852).

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abstract = "Colony stimulating factor (CSF) was initially named for the activity or factor which modulated colony formations of mature granulocytes originated from a progenitor cell in bone marrow in a culture dish. In this article, we described a detective system for CSF, CSF-producing tumor which strongly suggested to us that CSF was not only a factor in vitro phenomenon but also a factor working actually in vivo. Finally, we presented a few experiences of administration of recombinant CSF to experimental animals and finally several cases of clinical trials of CSF which seem to be very potent and able agents for granulopenic patients.",

author = "Y. Niho and S. Okamura and M. Harada and T. Shibuya and N. Kimura and T. Tanaka and K. Akashi",

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editor = "M. Torisu and T. Yoshida and M. Torisu and T. Yoshida",

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AU - Niho, Y.

AU - Okamura, S.

AU - Harada, M.

AU - Shibuya, T.

AU - Kimura, N.

AU - Tanaka, T.

AU - Akashi, K.

PY - 1989

Y1 - 1989

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AB - Colony stimulating factor (CSF) was initially named for the activity or factor which modulated colony formations of mature granulocytes originated from a progenitor cell in bone marrow in a culture dish. In this article, we described a detective system for CSF, CSF-producing tumor which strongly suggested to us that CSF was not only a factor in vitro phenomenon but also a factor working actually in vivo. Finally, we presented a few experiences of administration of recombinant CSF to experimental animals and finally several cases of clinical trials of CSF which seem to be very potent and able agents for granulopenic patients.

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M3 - Conference contribution

AN - SCOPUS:0024853278

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T3 - New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852

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EP - 521

BT - New horizons of tumor immunotherapy

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A2 - Yoshida, T.

A2 - Torisu, M.

A2 - Yoshida, T.

PB - Elsevier Science Publishers B.V.

T2 - The International Symposium on new horizons of tumor immunotherapy

Y2 - 30 November 1988 through 2 December 1988

ER -

Colony-stimulating factor - in vitro and in vivo effect

Abstract

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Other

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