Colony-stimulating factor - in vitro and in vivo effect

Y. Niho, S. Okamura, M. Harada, T. Shibuya, N. Kimura, T. Tanaka, K. Akashi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Colony stimulating factor (CSF) was initially named for the activity or factor which modulated colony formations of mature granulocytes originated from a progenitor cell in bone marrow in a culture dish. In this article, we described a detective system for CSF, CSF-producing tumor which strongly suggested to us that CSF was not only a factor in vitro phenomenon but also a factor working actually in vivo. Finally, we presented a few experiences of administration of recombinant CSF to experimental animals and finally several cases of clinical trials of CSF which seem to be very potent and able agents for granulopenic patients.

Original languageEnglish
Title of host publicationNew horizons of tumor immunotherapy
Subtitle of host publicationproceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852
EditorsM. Torisu, T. Yoshida, M. Torisu, T. Yoshida
PublisherElsevier Science Publishers B.V.
Pages501-521
Number of pages21
ISBN (Print)0444813489
Publication statusPublished - Dec 1 1989
EventThe International Symposium on new horizons of tumor immunotherapy -
Duration: Nov 30 1988Dec 2 1988

Publication series

NameNew horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852

Other

OtherThe International Symposium on new horizons of tumor immunotherapy
Period11/30/8812/2/88

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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  • Cite this

    Niho, Y., Okamura, S., Harada, M., Shibuya, T., Kimura, N., Tanaka, T., & Akashi, K. (1989). Colony-stimulating factor - in vitro and in vivo effect. In M. Torisu, T. Yoshida, M. Torisu, & T. Yoshida (Eds.), New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852 (pp. 501-521). (New horizons of tumor immunotherapy: proceedings of the International Symposium on new horizons of tumor immunotherapy. ICS852). Elsevier Science Publishers B.V..