Color representation is retinotopically biased but locally intermingled in mouse V1

Shuhei Aihara, Takashi Yoshida, Takayuki Hashimoto, Kenichi Ohki

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Dichromatic vision is common in many mammals. However, color processing in the primary visual cortex (V1) of dichromatic mammals is relatively unknown compared to the trichromatic primates. In this study, we investigated the functional organization of color processing in mouse V1. The mouse retina has a graded expression pattern of two opsins along its dorsoventral axis. However, it is not clear whether and how this expression pattern is reflected in the cortical representation at local (several hundred microns) and areal (V1) level. Using in vivo two-photon calcium (Ca2+) imaging and wide-field Ca2+ imaging, we revealed that V1 neurons responded to S (UV)- and M (green)-opsin isolating stimuli with slightly biased color preference depending on retinotopic position in V1. This was consistent with the distribution of retinal opsins. At the cellular level, preferences for S- and M-opsin isolating stimuli were intermingled in a local region encompassing several hundred microns. These results suggest that functional organizations of color information are locally intermingled, but slightly biased depending on the retinotopic position in mouse V1.

Original languageEnglish
Article number22
JournalFrontiers in Neural Circuits
Volume11
DOIs
Publication statusPublished - Mar 29 2017

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Opsins
Color
Mammals
Visual Cortex
Photons
Primates
Retina
Calcium
Neurons

All Science Journal Classification (ASJC) codes

  • Neuroscience (miscellaneous)
  • Sensory Systems
  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

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Color representation is retinotopically biased but locally intermingled in mouse V1. / Aihara, Shuhei; Yoshida, Takashi; Hashimoto, Takayuki; Ohki, Kenichi.

In: Frontiers in Neural Circuits, Vol. 11, 22, 29.03.2017.

Research output: Contribution to journalArticle

Aihara, Shuhei ; Yoshida, Takashi ; Hashimoto, Takayuki ; Ohki, Kenichi. / Color representation is retinotopically biased but locally intermingled in mouse V1. In: Frontiers in Neural Circuits. 2017 ; Vol. 11.
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